Locally Advanced / Metastatic Solid Tumors

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Review clinical trials related to Locally Advanced / Metastatic Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

SI-B036-ST-101 in Advanced/Metastatic Solid Tumors

The objective of the study is to evaluate the safety and tolerability of SI-B036 in participants with solid tumors who have received at least one prior line of therapy for advanced disease.

Participants needed: 424
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: SystImmune Inc.Updated: Oct 5, 2026Locations: 7
Eligibility criteria

Documented locally advanced or metastatic solid tumor(s) not amenable to curativ... [+3]

Chemotherapy, biological therapy, immunotherapy, targeted therapy (including sma... [+21]

Status: Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.

Participants needed: 290
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Crescent Biopharma, Inc.Updated: Sep 10, 2026Locations: 31
Eligibility criteria

Life expectancy ≥ 3 months [+12]

Has malignancies other than disease under study within the past 3 years [+12]