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Locally Advanced or Metastatic Solid Tumors With PIK3CA-mutated

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Review clinical trials related to Locally Advanced or Metastatic Solid Tumors With PIK3CA-mutated. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

GenSci145 as Monotherapy or in Combination Therapy, in Participants With PIK3CA-mutated, Locally Advanced or Metastatic Solid Tumors.

An international, multicenter, open-label, Phase 1/2 clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics, and efficacy of GenSci145, as monotherapy or in combination therapy, in participants with PIK3CA-mutated, locally advanced or metastatic solid tumors.

Participants needed: 186
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Changchun GeneScience Pharmaceutical Co., Ltd.Updated: Sep 25, 2026Locations: 1
Eligibility criteria

Participants should be able to understand and voluntarily sign a written ICF (be... [+28]

Any active malignancy ≤ 2 years prior to the first dose of GenSci145, except for... [+7]

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