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Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC)

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Review clinical trials related to Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC

This is a phase II, open-label study to assess the efficacy of AZD2936 in terms of molecular residual disease (MRD) clearance and treatment outcome in patients with MRD after definitive treatment for high risk locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC). MRD is defined as ctDNA detection in plasma after definitive treatment. Approximately 100 patients are expected to be enrolled.

Participants needed: 102
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: University Health Network, TorontoUpdated: Oct 5, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years at the time of screening or age of consent according to law. [+20]

Histological or cytologically confirmed head and neck cancer of any other primar... [+29]

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