Long-Term Care

6

Review clinical trials related to Long-Term Care. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Long-Term Recovery and Quality of Life in Sepsis Survivors

The goal of this observational study is to learn about the long-term outcomes and recovery of adult patients admitted to the intensive care unit (ICU) with sepsis. The main questions it aims to answer are: * Which patient-related, infection-related and centre-level factors (for example type of pathogen, time to adequate antibiotic therapy, and local sepsis management practices) are associated with poor quality of life six months after ICU admission for sepsis? * How do these factors influence other patient-centred outcomes, such as mortality, psychological and cognitive recovery, functional status and return to work? This is an international, multicentre, prospective observational cohort study. It will consecutively enrol adult patients (18 years or older) admitted to participating ICUs with sepsis, diagnosed by the treating clinician at ICU admission and, where locally available, meeting Sepsis-3 criteria. Participants will: * have clinical data collected from their medical records at ICU admission, on day 7 and at ICU discharge (infection characteristics, organ support, antibiotic therapy, delirium, rehabilitation and centre organisation); * be followed at 28 days (medical record review, or telephone contact if already discharged) and contacted by telephone at 3 months and 6 months after ICU admission for structured assessment of quality of life, psychological and cognitive recovery, functional status, return to work and healthcare utilisation. The study plans to enrol 600 patients in participating ICUs across several countries, coordinated by Geneva University Hospitals (HUG). Findings will help identify modifiable factors that may improve long-term recovery and guide future interventions for sepsis survivors.

Participants needed: 530
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University of Geneva, SwitzerlandUpdated: Oct 7, 2026Locations: 1Duration: 6 Months
Eligibility criteria

Adults aged 18 years or older [+1]

Refusal to participate, by the patient or the legal representative [+3]

Status: Not yet recruiting

Assistive Device Rental/Purchase, LTC Service Use, and Caregiver Burden in Taiwan

The goal of this observational study is to examine the associations between assistive device approval and acquisition modality (rental or purchase), long-term care service utilization, and family caregiver burden among individuals receiving long-term care services in Taiwan. The study will use de-identified nationwide long-term care administrative data from 2021 to 2022. The main questions it aims to answer are: 1. What individual, disability-related, socioeconomic, residential, and caregiving factors are associated with assistive device approval, the number and type of approved devices, and rental or purchase modality? 2. Are assistive device approval and utilization patterns associated with the use of formal long-term care services and with family caregiver burden?

Participants needed: 161,771
Trial details
Biological sex: AllType: ObservationalSponsor: National Health Research Institutes, TaiwanUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

Individuals with a valid long-term care case record (CA100) in Taiwan's long-ter... [+3]

Records with missing key linkage variables that prevent establishment of relatio... [+4]

Status: Recruiting

Effectiveness of Implementing a Reablement Model in Community-Based Long-Term Care Centers

This study will examine whether a reablement approach can help people receiving community-based long-term care maintain or improve their independence, daily functioning, and quality of life. Approximately 300 adults from eight long-term care facilities across Taiwan will participate. The 12-week reablement program includes group and individualized activities designed to support mobility, cognitive function, daily activities, and social participation. Participants' physical and cognitive function, daily living abilities, emotional well-being, quality of life, and personal goals will be assessed before and after the program. The study will also include observations and interviews with care providers, participants, and family members to understand their experiences with the program and identify factors that support successful implementation. The findings are expected to help develop a practical reablement model for community-based long-term care in Taiwan and provide guidance for improving care quality, independence, and healthy aging.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: National Taiwan University HospitalUpdated: Aug 20, 2026Locations: 8
Eligibility criteria

Aged 18 years or older and assessed as CMS Level 2 or above. [+2]

Severe cognitive impairment or severe visual or hearing impairment that interfer... [+3]

Status: Recruiting

Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce

This project will compare two training models of an evidence-based online dementia care training program for direct care staff in assisted living to a waitlist control: 1) essentiALZ training and 2) essentiALZ training + Project ECHO. It will examine the extent to which each model is implemented and achieves its intended outcomes to improve staff knowledge and attitudes, change care practices, and improve the wellbeing of staff, residents, and residents' family members. Results will inform next steps in dementia care training for the assisted living (AL) and broader long-term care workforce. To examine these outcomes, data will be collected from AL staff and families over the course of 6 months. Staff will complete questionnaires and participate in interviews (as applicable) at baseline, post-training, 3-months, and 6-months. Families will participate in interviews at baseline, 3-months, and 6-months.

Participants needed: 1,764
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of North Carolina, Chapel HillUpdated: Apr 13, 2026Locations: 1
Eligibility criteria

Staff (part-time, full-time, and including contract staff) who provide direct ca... [+8]

Status: Not yet recruiting

A Path to Prevention of Elder Abuse in Long-term Care. Prevalence Study Among Staff in Long-term Care.

Globally, studies indicated that 16% of community dwelling older adults have been exposed to some form of abuse in the past 12 months. Furthermore, a global meta-analysis about AOP in long-term care facilities used staff as respondents and found that the pooled estimate of overall self-reported perpetration of staff to resident abuse during the past 12 months was 64.2% (95% CI 53.3-73.9%). Similar findings was also reported in a study from Norway in which the overall prevalence of observed staff-to-resident abuse was 76% and 60% of respondents report self-perpetration of abusive acts during the past 12 months. Resident-to-resident aggression was even more common, observed by 88% of respondents. This study is part of the Swedish national research program APPEAL (A Path to Prevention of Elder Abuse in Long-term care) with the long-term goal to co-create an intervention for abuse of older people (AOP) in nursing homes together with stakeholders, i.e., staff, managers, care recipients and relatives. Study design and data collection: A cross-sectional study design will be used with slightly different data collection modes. 1. Population sample. Statistics Sweden combine data from the Swedish Occupational Register with data about industry codes (SNI-codes) to make a national randomized sample of staff working in home care services (n=12000) and nursing homes (n=11000) in Sweden. Data will be collected through a digital survey. Data will be combined with available register data from Statistics Sweden, including for example sex, age, civil state and occupational related data. 2. Workplace sample. Sweden has 290 Municipalities. The Swedish Association of Local Authorities and Regions (SALAR) have an official categorization of the municipalities based on e.g., urban area size, proximity to a larger urban area, and commuting patterns. One municipality in each of the nine categories has been randomly selected for participation. In the randomization process, geographical location of the municipalities has been considered to assure national representativeness, meaning that in case several municipalities in the same geographical region were selected a new randomization was conducted. Staff in each selected municipalities will be invited to participate through managers in each organization. Data will be collected through a digital questionnaire. Organizations will be encouraged to set a side time at a staff meeting for completing the questionnaire. If this is not possible, a link to the questionnaire will be sent out by e-mail. Data will be collected anonymously. Material: The questionnaire used in the previously mentioned Norwegian study about AOP in long-term care facilities has been translated and culturally adapted. In addition, items about background characteristics of respondents as well as risk factors for AOP on both an individual and system level are included, e.g., workload and perceived support at the workplace and ageist attitudes. Analysis: Primary outcomes will be proportion of staff reporting different types of abuse (psychological, physical, sexual, financial abuse and neglect) in different relational contexts, i.e., self-perpetrated, staff-to-resident and relative-to resident abuse, and in long-term care facilities resident-to-resident abuse. Secondary outcome will be staff reported own exposure to different forms of abuse at the workplace, including by residents, co-workers, relatives and managers. Logistic regression analysis will be used to investigate associations between reporting different forms of abuse and potentially explanatory factors.

Participants needed: 6,000
Trial details
Age: 18-69Biological sex: AllType: ObservationalSponsor: Linkoeping UniversityUpdated: Mar 27, 2026Locations: 1
Eligibility criteria

Working in home care services or a long-term care facility in Sweden [+1]

None

Status: Recruiting

Holistic Self-Empowerment Care Intervention for Optimized Independent Living and Quality of Life: A Study Protocol

This protocol describes a pilot study evaluating the effectiveness of the Self-Empowerment Care Model in promoting independence and quality of life among frail older adults in Hong Kong. Rooted in Nordic re-enablement principles and refined in Japan, the intervention adopts a holistic approach that focuses on hydration, exercise, diet, and defecation care. This 12-week intervention will be tested across three care settings-residential, day care, and home care. The study uses a quasi-experimental design involving 60 participants, aiming to compare outcomes of the intervention group with a control group receiving standard care. The study also assesses its impact on caregivers' burden and job satisfaction.

Participants needed: 207
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Dec 17, 2024Locations: 1
Eligibility criteria

Age 65 years or older [+2]

Severe cognitive impairment, those with mild impairment will be considered. [+2]