Health Trials

Major Depressive Disorder With Anxious Distress

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Review clinical trials related to Major Depressive Disorder With Anxious Distress. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

This is a randomized, parallel-group, double-blind, placebo-controlled, monotherapy study to evaluate the efficacy, safety, and tolerability of SPT-300 (GlyphAllo) in adults with major depressive disorder (MDD), with or without anxious distress.

Participants needed: 360
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Seaport TherapeuticsUpdated: Aug 17, 2026Locations: 62
Eligibility criteria

Participant is a male or female between 18 and 65 years of age, inclusive willin... [+5]

any depressive episode with psychotic or catatonic features. [+12]

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