Malocclusion, Angle Class II

4

Review clinical trials related to Malocclusion, Angle Class II. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time

The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I osteotomy for jaw correction. The main questions it aims to answer are: * Do 3D-printed patient specific titanium plates improve surgical accuracy (as measured by ability to transfer the computer plan to the patient's jaw)? * Do 3D-printed patient specific titanium plates decrease operative time when compared to milled patient specific titanium plates? This study will compare two groups of patients. One group will receive 3D printed plates (study group) and the other will receive milled plates (control group) to see if the different methods of making the plates changes the surgical accuracy or operative time. All participants in the study will: * Have Le Fort I osteotomy surgery using patient specific titanium plates (either 3D printed or milled). * Have CT scans before and after surgery to evaluate accuracy. Have their operative time recorded. * Have a post-surgical follow-up to evaluate healing, stability and orthodontic treatment.

Participants needed: 12
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Future University in EgyptUpdated: Sep 25, 2026Locations: 1
Eligibility criteria

Skeletally mature patients (typically ≥ 18 years old) with fused growth plates. [+4]

Patients who refused to be included in the research and patients unable to compl... [+5]

Status: Recruiting

Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates

Patients with skeletal class II malocclusion who have a retracted lower jaw will be treated in this study. The efficacy of clear Plates in the treatment of Skeletal Class II Malocclusion will be assessed. The skeletal, dental and soft tissues changes resulted by this intervention will be studied and compared with the results of Traditional treatment with fixed appliances.

Participants needed: 32
Trial details
Age: 10-13Biological sex: AllType: InterventionalSponsor: Hama UniversityUpdated: Sep 16, 2026Locations: 1
Eligibility criteria

- Patients with mixed dentition at age 10.5-13 years. [+5]

-Patients with periodontal disease. [+8]

Status: Not yet recruiting

3D Printed Occlusal Splints for Intraoperative Use

A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery. This alignment further places maxilla and mandible into proper position. An occlusal splint contains outlines maxillary and mandibular dentition allowing the teeth to lock into place with correct alignment. At Johns Hopkins, traditionally hand-made and industry-made 3D printed splints have been used safely. However, prior studies have demonstrated the ability of in-house 3D prints to save time and money compared to industry. In-house models are similarly produced with FDA-clear, biocompatible resin for 3D printing, and maintain equivalent safety for patients compared to industry-made models.

Participants needed: 70
Trial details
Age: 0-80Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Aug 11, 2026
Eligibility criteria

Patients of any age who require any orthognathic surgery (including, but not lim...

Patients who are non-English speaking. [+1]

Status: Not yet recruiting

Therapeutic Effects of Class II Elastics on Aligners in Different Vertical Skeletal Patterns

The objective is to compare the dento-alveolar therapeutic effects of wearing class II inter-arch traction elastics on aligners versus multi-brackets in an adult population. The principal hypothesis is no significant difference in therapeutic effects of using inter-arch elastics on aligners versus multi-brackets.

Participants needed: 80
Trial details
Age: 13+Biological sex: AllType: ObservationalSponsor: Central Hospital, Nancy, FranceUpdated: Jul 23, 2024Locations: 1
Eligibility criteria

CVM stage 5 on lateral teleradiography (end of growth) [+3]

Incomplete data [+3]