Malocclusions

5

Review clinical trials related to Malocclusions. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device

Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Semmelweis UniversityUpdated: Sep 24, 2026Locations: 1
Eligibility criteria

Age 18 years or older (skeletally mature patients) [+4]

History of previous orthognathic or major craniofacial surgical interventions [+7]

Status: Recruiting

Changes in Depression and Esthetic Perception After Orthognathic Surgery

This study aims to evaluate changes in depressive symptoms and subjective esthetic perception before and after bimaxillary orthognathic surgery in patients with different types of malocclusion. The study will analyze anonymized clinical data and questionnaire responses to assess the impact of orthognathic surgery on psychological well-being and esthetic perception.

Participants needed: 18
Trial details
Age: 18-40Biological sex: AllType: ObservationalSponsor: Kırıkkale UniversityUpdated: Jul 16, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 40 years. [+6]

Patients without an indication for bimaxillary orthognathic surgery or those und... [+5]

Status: Recruiting

Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction

To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial

Participants needed: 16
Trial details
Age: 13-20Biological sex: AllType: InterventionalSponsor: Al-Azhar UniversityUpdated: Mar 6, 2026Locations: 1
Eligibility criteria

Orthodontic patients referred for therapeutic extraction of bilateral maxillary... [+5]

Patients with impacted canines. [+3]

Status: Not yet recruiting

Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy

The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment. It will compare the effects of vitamin D supplementation with a placebo to clarify its role in the aforementioned aspects of orthodontic care. The main questions it aims to answer are: How does vitamin D supplementation affect salivary opiorphin levels in patients undergoing fixed orthodontic mechanotherapy at Specialist Hospital Universiti Sains Malaysia? What is the impact of vitamin D supplementation on pain perception during fixed orthodontic mechanotherapy? How does vitamin D supplementation influence the rate and quality of tooth movement in patients undergoing fixed orthodontic mechanotherapy? What is the relationship between salivary opiorphin levels and pain perception in patients supplemented with vitamin D during fixed orthodontic mechanotherapy? How does vitamin D supplementation affect changes in alveolar bone density during fixed orthodontic mechanotherapy? Researchers will provide vitamin D to the experimental group while the control group receives a placebo to see if vitamin D intake has an impact on substances in saliva, pain, tooth movement, and the density of the bone around teeth during orthodontic treatment. Participants will: Take vitamin D or a placebo every day for 4 months Visit the clinic once every 4 weeks for checkups and tests Participate in the study for a duration of up to 4 months

Participants needed: 48
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Hospital Universiti Sains MalaysiaUpdated: Dec 23, 2025Locations: 1
Eligibility criteria

Age Range: 18 to 35 years old. This age group is common and suitable for orthodo... [+3]

Oral Local Problems: Patients with uncontrolled acute or chronic oral inflammati... [+3]

Status: Recruiting

Hyrax Vs. Invisalign Palatal Expander Clinical Study

The purpose of this study is to compare expansion result and the overall experience between the Invisalign Palatal Expander and the Hyrax expander.

Participants needed: 36
Trial details
Age: 6-11Biological sex: AllType: InterventionalSponsor: Align Technology, Inc.Updated: Dec 4, 2024Locations: 4
Eligibility criteria

Subject ages 6-11 years old [+2]

Subjects with palatal exostosis/surface aberration/ cleft palate [+2]