Meniscal Tears

5

Review clinical trials related to Meniscal Tears. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Needle Arthroscopy vs Conventional Arthroscopy in Knees

This is a pilot randomized controlled trial will have 54 participants. The purpose of this study is to compare two surgical techniques to determine the differences in postoperative pain and early recovery in patients between 18-65 years old with simple knee pathologies including meniscal tear, chondral lesions, and loose bodies. Patient-reported outcomes and operative efficiency will be also compared. The two surgical techniques we are comparing are: 1. NanoScope™ Needle Arthroscopy for the affected knee 2. Conventional Arthroscopy for the affected knee Patients will be randomized pre-operatively but final eligibility will be confirmed intra-operatively. The study assessors and data analysts will be blinded to the treatment group via limited access to surgical records and post-operative imaging. If patients consent to participate they will be asked to come to research visits at baseline (pre-operatively), at 2-weeks, 6-weeks, and 3-month post-operatively to complete a set of questionnaires including a demographic form, SANE score, IKDC Subjective, and the EQ-5D VAS Pain, Pain and Medication Logbook will be completed from the day of surgery until day 14, and a Rehabilitation Log will assess "Return to Activity/Work". A clinical assessment will include: Range of motion, effusion, and joint line tenderness. A pre-operative X-ray and MRI will be collected as standard of care. Patients will be remunerated with a maximum of $160 if they come to all research visits.

Participants needed: 54
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Panam ClinicUpdated: Sep 16, 2026
Eligibility criteria

• Clinical diagnosis of: Meniscal tears (Medial or Lateral) suitable for partial... [+3]

• Instability: Concomitant ACL, PCL, or multi-ligament injury requiring reconstr... [+12]

Status: Not yet recruiting

Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study

This prospective, randomized, comparative clinical study will evaluate the clinical and functional outcomes of meniscal repair augmented with intraoperative intralesional leukocyte-poor platelet-rich plasma (LP-PRP) compared with conventional meniscal repair without biological augmentation. A total of 62 participants aged 18 to 40 years undergoing meniscal repair will be assigned to either the LP-PRP group or the control group. Participants will be followed for 6 months after surgery. Clinical outcomes will include knee function assessed using the International Knee Documentation Committee (IKDC) questionnaire, pain intensity assessed using the Visual Analog Scale (VAS), time to return to usual activities, and adverse events or complications. Assessments will be performed preoperatively and during postoperative follow-up at 2 weeks, 1 month, 3 months, and 6 months.

Participants needed: 62
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Universidad Autonoma de Nuevo LeonUpdated: Sep 11, 2026Locations: 1
Eligibility criteria

Age 18 to 40 years, with confirmed skeletal maturity. [+4]

Metabolic or systemic diseases that may impair healing (e.g., uncontrolled diabe... [+7]

Status: Recruiting

A Nanoscopic Second Look Into the Knee Joint

The goal of this clinical trial is to look at how well different surgeries heal over time in patients that have previously undergone arthroscopic knee interventions. These procedures may include cartilage repair or grafting, meniscus repair or trimming, ligament reconstruction, cartilage smoothing, and treatments such as amniotic tissue or platelet rich plasma (PRP). Using a very small camera called a nanoarthroscope, doctors will take a "second look" inside the knee after surgery to see how it has healed. These findings will be compared to patient-reported outcomes, such as pain and function scores, as well as images taken during the original surgery. The goal is to determine whether this second look provides useful information that can help guide recovery and future care.

Participants needed: 15
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Angelina Vera MDUpdated: Jul 17, 2026Locations: 1
Eligibility criteria

Adults aged 18 years and older who have undergone or are scheduled to undergo ar... [+3]

Refusal to undergo postoperative in-clinic second-look nanoscopic arthroscopy of... [+4]

Status: Not yet recruiting

Effects of Pulsed Electromagnetic Field Therapy on Meniscal Healing, Symptom Relief, and Knee Function

The goal of this clinical trial is to learn if pulsed electromagnetic field (PEMF) combined with home exercise improves healing and function in adults with meniscus tears. The main questions it aims to answer are: 1. Does PEMF therapy help heal meniscus tears, as seen on MRI scans? 2. Does PEMF therapy subjectively reduce knee pain, improve movement, and enhance quality of life? 3. Does PEMF therapy objectively help patients perform daily activities more easily? Researchers will compare PEMF therapy against a sham (inactive) treatment to determine if it provides additional benefits. Participants will: * Be assigned randomly to either the PEMF group (active treatment) or the sham PEMF group (inactive, but identical in appearance) * Receive either real PEMF therapy or sham treatment twice a week for 8 weeks (each session lasts 10 minutes). * Follow a standard home exercise program to strengthen their knees. * Have their knee function, pain levels, and healing progress checked through MRI scans, questionnaires, imaging and physical tests. * Return for 3 follow-up visits after the 8-week treatment period.

Participants needed: 40
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Chinese University of Hong KongUpdated: Aug 12, 2025Locations: 1
Eligibility criteria

Male and female patients aged 18-60 [+5]

Congenital discoid meniscus confirmed by MRI [+10]

Status: Not yet recruiting

The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique

This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction. The study aims to assess the safety, efficacy, and functional improvements following these transplant procedures, utilizing donor tissues to restore joint function and alleviate pain in individuals with severe knee damage. Participants will undergo the transplantation procedure and be monitored for post-operative recovery, complications, and long-term outcomes, including joint stability and mobility. The study seeks to provide valuable insights into the effectiveness of these advanced surgical techniques for knee joint repair.

Participants needed: 200
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Beijing Tsinghua Chang Gung HospitalUpdated: Jul 28, 2025
Eligibility criteria

Aged 18-50 years [+4]

Severe tibiofemoral osteoarthritis (Kellgren-Lawrence grade ≥3) [+6]