Health TrialsbyHealthPanel

Metastatic Urothelial Cancer

3

Review clinical trials related to Metastatic Urothelial Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

BL-M07D1 (Trastuzumab Brengitecan T-bren) vs Standard of Care Platinum-based Chemotherapy (PBC) for HER2-expressing Metastatic Urothelial Cancer After Progression on Anti-PD-(L)1-based Therapy

The objective of the study is to evaluate the efficacy and safety of T-bren in participants with HER2 expressing metastatic UC with progression on or after anti-PD-(L)1-based therapy.

Participants needed: 520
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: SystImmune Inc.Updated: Oct 13, 2026Locations: 2
Eligibility criteria

Histologically or cytologically documented metastatic or surgically unresectable... [+8]

Prior topoisomerase inhibitor-based ADC therapy. [+12]

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Status: Recruiting

Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy

The goal of this study is to evaluate the feasibility and preliminary efficacy of a combined acupuncture and exercise intervention for the management of chemotherapy-induced peripheral neuropathy (CIPN) in participants with bladder cancer receiving enfortumab vedotin (EV) and pembrolizumab (Pembro). The names of the two study groups in this research study are: * Acupuncture + Virtual Exercise (AVE) * Virtual Exercise Only (VE)

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dana-Farber Cancer InstituteUpdated: Sep 10, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years old [+10]

History of documented grade 2 or greater peripheral or motor neuropathy prior to... [+10]

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Status: Recruiting

Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma

This phase 1/2 study will evaluate the maximum tolerated dose, efficacy, and safety of clofarabine in patients with advanced or metastatic urothelial cancer.

Participants needed: 50
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Ekaterina LaukhtinaUpdated: Jun 26, 2025Locations: 1
Eligibility criteria

Patients with histologically or cytologically confirmed urothelial carcinoma, ra... [+13]

Received previous treatment with clofarabine [+12]

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