Health Trials

Moderately Hypofractionated Radiotherapy

1

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Condition / disease
Location
Status: Not yet recruiting

Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II Trial

This study aims to observe and evaluate the efficacy and safety of moderately hypofractionated radiotherapy combined with chemotherapy and immunotherapy, compared with conventional neoadjuvant chemoradiotherapy, in patients with high-risk locally advanced colorectal cancer.

Participants needed: 165
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Fudan UniversityUpdated: Apr 14, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years and ≤ 75 years. [+6]

Presence of distant metastasis. [+11]

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