Neck Pain Musculoskeletal

15

Review clinical trials related to Neck Pain Musculoskeletal. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Changes in Cervical Posture, Cervical Function, and Neck Pain After Sleeve Gastrectomy

Obesity may contribute to neck pain, altered cervical posture, and impaired cervical function through increased mechanical loading, changes in body alignment, and reduced muscle performance. Although laparoscopic sleeve gastrectomy can produce substantial weight loss, its effects on cervical posture and neck-related function have not been studied comprehensively. This prospective, single-center study will include approximately 25 adults who are already scheduled to undergo laparoscopic sleeve gastrectomy as part of their routine clinical care. The decision to perform surgery and the surgical procedure itself will not be assigned or modified by the study. Participants will be evaluated before surgery and at 3, 6, and 12 months after surgery. Study assessments will include neck-related disability, neck pain intensity, quality of life, cervical range of motion, cervical muscle strength and endurance, and cervical joint position sense. Existing preoperative lateral cervical radiographs will be reviewed, and a lateral cervical radiograph will be obtained at the 12-month follow-up to assess cervical spinal alignment. The primary outcome will be the change in Neck Disability Index scores across the scheduled study assessments. The study aims to determine whether weight loss following laparoscopic sleeve gastrectomy is associated with changes in cervical posture, neck pain, and cervical function.

Participants needed: 25
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Haydarpasa Numune Training and Research HospitalUpdated: Sep 28, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 65 years [+5]

Previous cervical spine surgery [+6]

Status: Recruiting

Clinical and Brain Activity Assessment Before and After Physiotherapy in People With Chronic Non-specific Neck Pain

The goal of this clinical trial is to investigate whether electroencephalographic features are associated with the multidimensional clinical characteristics of adults with chronic non-specific neck pain and whether clinical and brain function measures change following physiotherapy. Participants with chronic non-specific neck pain will receive six weekly treatment sessions consisting of a manual physiotherapy and neck-specific exercise programme, including a home exercise programme. Clinical, psychophysical, and 64-channel electroencephalographic assessments will be performed at baseline and approximately one week after completion of the intervention. Clinical outcomes will also be reassessed 12 weeks after the last treatment session. Electroencephalographic recordings will be obtained while participants are seated comfortably and instructed to remain relaxed. EEG-derived measures will be examined in relation to pain intensity, neck-related disability, psychological and cognitive-affective factors, sleep quality, and psychophysical pain responses. Healthy participants without chronic neck pain will undergo a comparable baseline assessment to provide reference data for the interpretation of brain function in the clinical group.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Ander Cervantes BenítezUpdated: Sep 25, 2026Locations: 1
Eligibility criteria

Chronic non-specific neck pain (>3 months duration) [+1]

Concomitant neurological or psychiatric disease apart from depression (especiall... [+4]

Status: Not yet recruiting

Application Based Behavior Nudging Active Breaks Versus Conventional Ergonomic Education for Thoracic Mobility and Neck Pain in Office Workers

This study is about neck pain and upper-back movement in office workers. Sitting for long hours and working on computers can contribute to neck and upper-back discomfort. The study will compare two approaches: App-Based Active Breaks: An app will remind participants to take 1 minute movement breaks during their workday. Conventional Approach: Participants will receive ergonomic advice and exercises to do twice a day. The exercises include simple movements for the upper back, shoulders, and neck. Participants will be assessed for neck pain, neck disability, upper-back movement, muscle endurance, and work-related difficulties before and after the program. The active program will last 6 weeks, followed by a final assessment in week 8. Participation is voluntary, and participants can withdraw at any time. Their personal information will be kept confidential. The study aims to find out whether taking short, regular movement breaks with app reminders can help reduce neck pain and improve upper-back movement in office workers.

Participants needed: 64
Trial details
Age: 25-50Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Aug 28, 2026
Eligibility criteria

25-50 years, employed in call-center or IT support roles for ≥30 hours per week. [+4]

Specific neck pathology (cervical radiculopathy, myelopathy, fracture, malignanc... [+5]

Status: Not yet recruiting

Manual Therapy vs. Home Exercise in Myogenic TMD With Neck Pain

Temporomandibular disorders (TMD) are common musculoskeletal conditions affecting the jaw joint and surrounding chewing muscles. Myogenic TMD specifically involves muscle pain and dysfunction, which is frequently accompanied by chronic neck pain due to the close anatomical and neurophysiological connections between the jaw and the cervical spine. The purpose of this study is to compare the clinical effectiveness of two widely used physiotherapy interventions-a clinician-administered manual therapy protocol and a patient-conducted home exercise program-in individuals diagnosed with myogenic TMD and chronic neck pain. The main research question is to determine whether targeted manual therapy applied to both the temporomandibular and cervical regions yields superior improvements in pain, jaw and neck mobility, quality of life, and masseter muscle properties compared to the Rocabado 6x6 home exercise program alone. 1. A total of 34 participants aged 18-45 years with myogenic TMD and chronic neck pain will be randomly allocated into two equal groups: Manual Therapy Group: Participants receive 6 individual treatment sessions (3 days per week for 2 weeks) consisting of soft tissue mobilization, trigger point therapy, myofascial release, and joint mobilization techniques applied to the jaw and neck regions. 2. Exercise Group: Participants perform the standardized Rocabado 6x6 home exercise program 3 days per week for 2 weeks, with adherence monitored through daily exercise diaries. All participants undergo comprehensive assessments at baseline and immediately following the 2-week intervention. Evaluated parameters include jaw and neck pain intensity (Visual Analog Scale), cervical and mandibular range of motion, cervical joint position sense, jaw proprioception, facial asymmetry, bruxism, TMD severity, movement-related fear (kinesiophobia), and quality of life. In addition, masseter muscle thickness and elasticity are objectively assessed using ultrasound imaging and elastography. The findings of this trial aim to provide healthcare professionals with high-level evidence regarding effective, targeted physiotherapy strategies for managing myogenic TMD co-occurring with cervical pain.

Participants needed: 34
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Pamukkale UniversityUpdated: Aug 25, 2026
Eligibility criteria

Presence of TMJ pain at rest, [+3]

Any orthopedic and/or neurological condition that would preclude the assessments... [+7]

Status: Not yet recruiting

Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache

The purpose of this study is to compare the effects of manual therapy and a multicomponent exercise program on suboccipital muscle thickness, joint position sense, pain, central sensitization, balance, and kinesiophobia in patients diagnosed with cervicogenic headache. Cervicogenic headache is a common secondary headache originating from dysfunction in the upper cervical spine. Dysfunction in the deep neck muscles, impaired neck joint awareness, and heightened pain sensitivity (central sensitization) are frequently observed in these patients. While both manual therapy and targeted exercise are used in physiotherapy practice, evidence regarding their direct comparative effects on suboccipital muscle morphology and somatosensory parameters remains limited. Participants will be randomly assigned to one of two treatment groups for a duration of 4 weeks (12 sessions total): 1. Manual Therapy Group: Receives joint mobilization, myofascial release, trigger point release, and suboccipital distraction targeting the cervical region. 2. Multicomponent Exercise Group: Receives deep cervical flexor strengthening, cervical proprioception training, head-eye coordination training, and progressive balance exercises. The main questions the study aims to answer are: * Do manual therapy and multicomponent exercise improve suboccipital muscle thickness and cervical joint position sense in patients with cervicogenic headache? * Is there a significant difference between manual therapy and multicomponent exercise in reducing pain intensity, central sensitization, disability, and fear of movement (kinesiophobia)? It is hypothesized that both intervention protocols will yield significant clinical improvements, with specific synergistic adaptations in muscle structure, somatosensory system processing, and pain-related fear.

Participants needed: 32
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Pamukkale UniversityUpdated: Aug 24, 2026
Eligibility criteria

Diagnosis of cervicogenic headache by a specialist physician, [+3]

History of head or neck surgery, [+11]

Status: Recruiting

Core Stability vs Scapular Stabilization on Hand Grip Strength in Chronic Myofascial Neck Pain

Chronic myofascial neck pain (CMNP) is a painful non-articular musculoskeletal neck syndrome that is a persistent and prevalent with a high incidence of recurrence rate range 30-93%.Management of myofascial trigger points were directed at its deactivation, and prevention of its recurrence. Based on mechanical kinetic chain, the upper extremity functions as a unique system of connected segments those collaborated in a harmony in order to perform daily life activities. Core stability exercises maximize motor pathways mechanoreceptors' activities, as well scapular stabilization exercises are generally recommended based on reported benefits in terms of chronic neck pain. The relationship between chronic myofascial neck pain, and hand disability is quite strong. From mechanical point of view, core stability exercises improve trunk stability in line to enhance upper extremity efficiency that facilitates hand, and pinch grasping. In addition, scapular stabilization exercises could improve both hand, and pinch grasp strength and dexterity. Therefore, this randomized clinical trial will be conducted in line to clarify the superiority of the therapeutic effects between core stability exercises, scapular stabilization exercises, and conventional physical therapy program on hand grip strength, pinch grip strength, neck pain intensity level, pain pressure threshold, and whole upper extremity functional level in patients with chronic myofascial neck pain.

Participants needed: 60
Trial details
Age: 25-45Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jul 10, 2026Locations: 1
Eligibility criteria

Patients diagnosed with chronic myofascial neck pain depending on referral, and... [+7]

Presence of signs of severe pathology such as malignancies, mainly of the cervic... [+8]

Status: Recruiting

Mobilization Techniques for Nonspecific Neck Pain: Effects on Cervical Endurance and Function

This clinical study investigates the comparative effects of two manual therapy mobilization techniques, Positional Release Technique (PRT) and Instrument-Assisted Soft Tissue Mobilization (İASTM), on cervical muscle endurance and functional performance in individuals with nonspecific neck pain. Nonspecific neck pain is a common musculoskeletal condition among office workers and students, often associated with poor posture, prolonged sitting, and repetitive strain. It leads to reduced muscle endurance, impaired functional capacity, and decreased quality of life. Early and effective management strategies are essential to prevent chronicity and disability. A total of 51 participants will be recruited and randomly assigned into three groups: Group 1 will receive PRT combined with a standardized home exercise program, Group 2 will receive İASTM combined with the same home exercise program, and Group 3 will serve as the control group receiving only conventional home exercise. The interventions will be delivered over a period of 4 weeks, with three sessions per week, under the supervision of trained physiotherapists. The home exercise program includes stretching, strengthening, and posture correction exercises designed to support cervical spine health. The primary outcomes of the study are cervical muscle endurance and functional performance, measured using validated clinical tests. Secondary outcomes include pain intensity assessed by the Visual Analog Scale (VAS), functional disability measured by the Neck Disability Index (NDI), health-related quality of life assessed by the SF-12 questionnaire, and work-related performance indicators. Assessments will be conducted at baseline and after 4 weeks of intervention. Randomization and blinding procedures will be applied to minimize bias, and standardized protocols will ensure consistency across groups. The main objective of this study is to determine whether the early application of PRT or İASTM, in combination with home exercise, provides superior improvements in cervical muscle endurance, pain reduction, and functional outcomes compared to exercise alone. By comparing these two mobilization techniques, the study aims to contribute evidence-based knowledge to physiotherapy practice and guide clinicians in selecting effective manual therapy approaches for nonspecific neck pain. The findings are expected to support clinical decision-making, improve patient care, and enhance rehabilitation strategies for individuals suffering from neck pain in occupational and daily life contexts.

Participants needed: 51
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Istanbul University - CerrahpasaUpdated: May 28, 2026Locations: 1
Eligibility criteria

Healthy individuals aged 18-40 years [+3]

History of neck trauma, surgery, or any cardiovascular, metabolic, neurological,... [+3]

Status: Recruiting

Osteopathic Manipulative Treatment vs Physiotherapy in Cervicocranial Dysfunction

This study aims to compare the effects of osteopathic manipulative treatment and standard physiotherapy in patients with cervicocranial dysfunction. The study will evaluate outcomes including dizziness, headache impact, neck disability, and psychological stress. Participants will be randomly assigned to one of two groups: osteopathic treatment or standard physiotherapy. The interventions will be applied over a defined treatment period, and outcomes will be measured before and after the intervention. The purpose of this study is to determine which approach is more effective in improving symptoms and functional outcomes in patients with cervicocranial dysfunction.

Participants needed: 50
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Burim PeliUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Age between 18 and 65 years. [+6]

Clinically confirmed vestibular disorders. [+6]

Status: Not yet recruiting

Neck Musculoskeletal Symptoms Among Turkish Endodontists

This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists. Endodontists are exposed to prolonged static postures and repetitive movements during clinical procedures, which may increase the risk of neck-related disorders. Participants will be asked to complete questionnaires regarding demographic characteristics, occupational factors, ergonomic conditions, and neck pain. In addition, physical assessments including cervical range of motion, muscle strength, endurance, posture, and proprioception will be performed using validated measurement tools. The study also aims to identify factors associated with neck pain, such as working conditions, posture, and clinical experience. The findings may help improve preventive strategies, ergonomic recommendations, and rehabilitation approaches for dental professionals.

Participants needed: 120
Trial details
Age: 25-65Biological sex: AllType: ObservationalSponsor: Atlas UniversityUpdated: Apr 8, 2026Locations: 1
Eligibility criteria

Aged 25 to 65 years [+3]

History of cervical spine surgery within the last 3 months [+6]

Status: Not yet recruiting

Effect of Body Mind Exercises and Specific Neck Exercises in Chronic Mechanical Neck Pain

To investigate the effect of body mind exercise and specific neck exercises in chronic mechanical neck pain on neck pain severity, functional disability, neck flexion range of motion, isometric neck muscle strength and quality of life.

Participants needed: 80
Trial details
Age: 50-65Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Adults aged between 50-65 years [+2]

History of cervical surgery [+3]

Status: Not yet recruiting

The Effectiveness of Dynamic Neuromuscular Stabilization (DNS) Exercises Compared to Localized Exercises and Standard Care on Pain Intensity, Neck Dysfunction, and Upper Cervical Range of Motion in Patients With Chronic Neck Pain: A Pilot Randomized Controlled Trial (RCT)

Many people experience long-lasting neck pain, which can affect daily life, work, and overall well-being. This study aims to find out which type of exercise program is most effective in reducing neck pain, improving neck movement, and making daily activities easier. What Is Being Studied?: The study compares three different types of treatment: DNS Exercises (Dynamic Neuromuscular Stabilization): Whole-body exercises focusing on posture, breathing, and core stability. Localized Neck Exercises: Targeted exercises for the neck and shoulder muscles. Standard Care: Usual physiotherapy treatment commonly provided in clinical practice. Study Procedures: Participants are randomly assigned to one of the three groups. Each participant receives individual exercise instruction from a physiotherapist. Participants are also given simple home exercises to perform on their own. The study lasts for about 12 weeks. What Will Be Measured?: At the beginning, during, and at the end of the study, the following will be assessed: Neck pain intensity (pain scale) Neck range of motion How much the pain affects daily life and activities Possible Benefits: Participants may experience: Less neck pain Improved neck mobility Better overall body awareness Even if not every participant notices improvement, taking part will help researchers improve future treatment options for chronic neck pain. Risks: No major risks are expected. All exercises are supervised by qualified physiotherapists and adjusted to each participant's abilities. Participation can be stopped at any time if discomfort or pain occurs. Voluntary Participation and Data Privacy: Participation is completely voluntary. All personal data will be kept confidential and analyzed anonymously for research purposes only. Participants may withdraw from the study at any time without any disadvantages.

Participants needed: 45
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Hochschule OsnabruckUpdated: Feb 9, 2026
Eligibility criteria

between 18 and 50 years of age. This ensures a homogeneous population that in-cl... [+3]

Cancer [+9]

Status: Not yet recruiting

Musical Mindfulness for Pain in the ED Waiting Room

Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. However, with the current ongoing opioid epidemic, it is important to consider other methods, both pharmacologic and nonpharmacologic, of pain reduction. Jazz music specifically has been demonstrated to have therapeutic effects on pain that can be used to lower the quantity of opioids administered to patients. Non-pharmacological interventions in the emergency department for pain typically consist of splinting an injury, applying heat or cold, or various distractions following initial and sequential pain assessment. Pharmacological interventions for pain in the Emergency Department involve the administration of acetaminophen, muscle relaxers, topical anesthetics, opioids, to name a few. In the emergency department (ED), providers are increasingly hesitant to prescribe opioids over the past decade due to the current opioid epidemic, in which there is an increasing proportion of people that develop an addiction to opioids, including those that are prescribed to them for pain management.. While emergency medicine providers' decrease in opioid prescriptions pertains to their implementation of opioid-prescribing policies, little evidence has been found demonstrating a direct link in these policies to decreases in substance misuse. Consequently, providers find themselves needing to become ingenious in their approach to pain in patients through the integration of pharmacologic and non-pharmacologic mediums of analgesia. A recent randomized controlled trial (RCT) from Brigham and Women's Hospital in Boston sought to identify the qualitative responses from patients in the ED following the arbitrary distribution of either supervised or unsupervised music therapy over a time period of 4 hours. The initial results found that, generally speaking, music therapy may lower reported pain and anxiety scores. Furthermore, stronger results were identified in case subjects with higher initial reports of pain via a pain catastrophizing scale, implying that a higher baseline of pain results in more relief from music therapy. One shortcoming in the article is the lack of analysis with reported results and the biopsychosocial model of pain. Heavy emphasis is placed on the psychological and social components of pain in the Brigham and Women's article through the implementation of the Pain Catastrophizing Scale and Brief Pain Inventory scoring done during the RCT, but no focus on linked biological changes in the subjects through the music therapy intervention. The purpose of this study is to (i.) assess the effect of a video training about musical pain management followed by a 15-minute music listening intervention on self-reported pain scores in ED patients with neck and back pain. The investigators also aim to (ii.) evaluate patient satisfaction and emotional response following the intervention. Opioid medications are commonly used to reduce substantial pain, and music therapy has been found to reduce associated pain and anxiety in patients, then the use of music therapy could be an aid in medicine to reduce opioid intake. The investigators hypothesize that the usage of a training on musical pain management combined with a specified jazz musical intervention will produce a significantly lower measured pain score in comparison to a video on mindful pain management followed by the patient's choice of activities.

Participants needed: 60
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: University of California, IrvineUpdated: Feb 6, 2026Locations: 1
Eligibility criteria

- Age >= 18 years old and <=75 years old [+1]

Status: Recruiting

Neck and Low Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica

The purpose of this study is to identify the prevalence of neck and low back pain in medical students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and to determine the outcome of a standardised spine exercise program on medical students experiencing neck and low back pain, using a prospective randomised control design.

Participants needed: 1,000
Trial details
Biological sex: AllType: InterventionalSponsor: The University of The West IndiesUpdated: Sep 10, 2025Locations: 2
Eligibility criteria

All students enrolled in the medical program at the University of the West Indie... [+2]

Individuals with a history of having spine surgery. [+2]

Status: Not yet recruiting

Effect of Kinesio Tape on Neck Pain in Lactating Women

This study will be conducted to investigate the effect of kinesio tape on neck pain in lactating women.

Participants needed: 60
Trial details
Age: 20-30Biological sex: FemaleType: InterventionalSponsor: Cairo UniversityUpdated: Mar 28, 2025Locations: 1
Eligibility criteria

All women are complaining from neck pain. [+3]

Cervical spondylosis. [+2]

Status: Recruiting

The Effects Of Oculomotor Exercises And Hands-On Protocol In Non-Specific Neck Pain

This study aimed to evaluate the effectiveness of adding oculomotor techniques and hands-on treatments to routine exercise protocols for individuals with non-specific chronic neck pain (NSCNP).

Participants needed: 38
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Yeditepe UniversityUpdated: Nov 4, 2024Locations: 1
Eligibility criteria

The inclusion criteria included being between ages 18 and 65 old, having been di...