Status: Not yet recruiting
Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma
This study is evaluating whether a weight-loss medication (PHEN/TOP) combined with healthy lifestyle counseling is safe, well tolerated, and can help reduce obesity in adolescents and young adults who are in remission from ALL, Hodgkin lymphoma, or non-Hodgkin lymphoma. Participants are randomly assigned to receive either PHEN/TOP plus counseling or counseling alone for 24 weeks and are followed for up to 52 weeks.
Participants needed: 100
Trial details
Phase: Phase 2Age: 12-24Biological sex: AllType: InterventionalSponsor: St. Jude Children's Research HospitalUpdated: Sep 23, 2026Locations: 1
Eligibility criteria
Participant has acute lymphoblastic leukemia (ALL), Hodgkin lymphoma, or non-Hod... [+6]
Participant has had recent, ongoing weight loss (≥5 kg in past 3-months). [+21]