Obesity; Impaired Glucose Regulation; Prediabetes; Type 2 Diabetes Mellitus

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Review clinical trials related to Obesity; Impaired Glucose Regulation; Prediabetes; Type 2 Diabetes Mellitus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Time-Restricted Eating and Staple Food Reduction Combined With App-Supported Exercise for Weight and Glycemic Control

This multicenter, three-arm randomized controlled trial will evaluate the effects of early time-restricted eating and staple food reduction, each combined with an app-supported exercise intervention, on body weight and glycemic control among adults with obesity and abnormal glucose metabolism. A total of 300 participants aged 18 to 50 years with BMI \>=28 kg/m2 and impaired glucose regulation or diabetes will be enrolled at five centers in China and randomized 1:1:1 to app-supported exercise alone, staple food reduction plus app-supported exercise, or early time-restricted eating plus app-supported exercise. The intervention lasts 12 weeks, followed by a 12-week post-intervention follow-up.

Participants needed: 300
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Peking UniversityUpdated: Jul 24, 2026
Eligibility criteria

Age 18 to 50 years, all sexes. [+5]

Secondary obesity, such as hypothyroidism or Cushing syndrome. [+9]