Obstructive Defecation Syndrome

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Review clinical trials related to Obstructive Defecation Syndrome. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of Low Level Laser Therapy on Women With Obstructive Defecation Syndrome

Obstructive defecation syndrome (ODS) is a condition in which a person has difficulty completely emptying the rectum during bowel movements. Women with ODS may experience excessive straining, a feeling of incomplete evacuation or blockage, abdominal discomfort, and the need to use manual assistance, laxatives, or enemas to facilitate defecation. This randomized controlled trial will investigate the effect of adding low-level laser therapy (LLLT) to a conventional treatment program for women with ODS. Participants will be randomly assigned to one of two groups. The control group will receive nutritional modification and biofeedback training, while the study group will receive the same treatment in addition to low-level laser therapy applied to the lumbosacral region. The study will evaluate whether adding low-level laser therapy can improve anorectal function, reduce the severity of ODS symptoms, and improve health-related quality of life compared with conventional treatment alone.

Participants needed: 40
Trial details
Age: 30-45Biological sex: FemaleType: InterventionalSponsor: Cairo UniversityUpdated: Aug 18, 2026Locations: 1
Eligibility criteria

Woman diagnosed with ODS according to the Renzi ODS score (≥ 9). [+4]

Any abnormalities around cancer colon, interstitial cystitis, or endometriosis. [+5]

Status: Recruiting

PEG3350 vs Senna After Urogyn Surgery

The goal of this study is to evaluate whether polyethylene glycol 3350 (PEG3350) versus senna is better at relieving postoperative constipation after urogynecologic surgery. The main questions it aims to answer are: What number of patients taking PEG3350 have obstructed defecation syndrome (ODS), a form of constipation, vs those taking senna in the week after urogynecologic surgery? What patient-level and procedure-level characteristics are associated with postoperative ODS, in patients taking PEG3350 vs senna? participants will: Take their randomized medication daily for seven days after surgery Fill out an ODS questionnaire before and one week after surgery Complete a daily bowel diary for 7 days after surgery

Participants needed: 254
Trial details
Phase: Phase 4Age: 18+Biological sex: FemaleType: InterventionalSponsor: St. Joseph's Health, New YorkUpdated: May 28, 2025Locations: 1
Eligibility criteria

Inclusion criteria includes women scheduled for urogynecologic surgery for pelvi...

Exclusion criteria include undergoing concomitant bowel surgery (colonic resecti...

Status: Not yet recruiting

Fat Injection for Rectocele Treatment: A Novel Approach

This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.

Participants needed: 25
Trial details
Age: 18-60Biological sex: FemaleType: InterventionalSponsor: Cairo UniversityUpdated: Sep 19, 2024
Eligibility criteria

Female patients aged between 18 and 60 years. [+3]

Patients who have previously undergone surgical repair of rectocele. [+5]