Ondansetron

4

Review clinical trials related to Ondansetron. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal Anesthesia

The aim of this prospective randomized double-blind study is to compare the effectiveness of routine antiemetic prophylaxis for the prevention of intraoperative nausea and vomiting (IONV) in non-fasted parturients undergoing emergency cesarean section under spinal anesthesia. Nausea and vomiting are common complications during cesarean delivery performed under spinal anesthesia and may negatively affect maternal comfort and perioperative safety. The incidence of these symptoms may be particularly increased in emergency cesarean sections involving non-fasted (full-stomach) parturients. This study compares two commonly used antiemetic strategies, namely 5-hydroxytryptamine-3 (5-HT3) receptor antagonists and dopamine receptor antagonists, to determine their relative effectiveness in preventing IONV during surgery. The findings are expected to contribute to optimization of antiemetic prophylaxis protocols, improvement of maternal comfort, and reduction of perioperative complications associated with nausea and vomiting during emergency cesarean delivery.

Participants needed: 100
Trial details
Phase: Phase 4Age: 18+Biological sex: FemaleType: InterventionalSponsor: Sanliurfa Education and Research HospitalUpdated: Aug 18, 2026Locations: 1
Eligibility criteria

Pregnant women scheduled for emergency cesarean delivery under spinal anesthesia [+5]

ASA physical status III or higher [+11]

Status: Recruiting

Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean Section

This study aims to compare the effect of ondansetron lozenge and intravenous for prevention of shivering in cesarean section (CS).

Participants needed: 90
Trial details
Age: 18-40Biological sex: FemaleType: InterventionalSponsor: Tanta UniversityUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Age from 18 to 40 years. [+2]

Parturient women with any contraindication or hypersensitivity to the study drug... [+8]

Status: Recruiting

Intravenous Versus Perineural Ondansetron for Laparoscopic Sleeve Gastrectomy

This prospective randomized non-inferiority study will be conducted to compare the analgesic anti-emetic effects of intravenous ondansetron versus perineural ondansetron in patients undergoing laparoscopic sleeve gastrectomy.

Participants needed: 482
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: May 15, 2026Locations: 1
Eligibility criteria

Patients of either sex [+3]

Allergy to experimental drugs. [+7]