Health TrialsbyHealthPanel

Opioid-induced Constipation

2

Review clinical trials related to Opioid-induced Constipation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation

The research objective is to characterize the risk of a major adverse cardiovascular event (MACE) among new users of naldemedine versus new users of lubiprostone and new users of naloxegol as comparator opioid induced constipation (OIC) medications.

Participants needed: 34,532
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: BioDelivery Sciences InternationalUpdated: Sep 30, 2026Locations: 1
Eligibility criteria

At least one dispensing of naldemedine or lubiprostone or naloxegol without prio... [+3]

Any acute MACE (non-fatal MI or non-fatal stroke) within six months before or on... [+2]

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Status: Not yet recruiting

Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain

This study is a prospective, single-arm, multicenter, real-world study to evaluate effect of bowel function, analgesic effect, quality of life, and safety of Mimeixin® in Chinese patients with severe cancer pain.

Participants needed: 203
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Henan Cancer HospitalUpdated: Mar 27, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years old, with a histological or pathological diagnosis of advanced ca... [+5]

Patients with contraindications to oxycodone/naloxone sustained-release tablets... [+3]

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