Pain and Anxiety

5

Review clinical trials related to Pain and Anxiety. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Effect of Virtual Reality Headsets on Pain, Anxiety, Patient Satisfaction, and Physiological Parameters in Patients Undergoing Open-Heart Surgery

This randomized controlled trial aims to investigate the effects of virtual reality headset use on pain, anxiety, patient satisfaction, and physiological parameters in patients undergoing open-heart surgery. Participants will be randomly assigned to two groups: the virtual reality group and the control group. Pain levels, anxiety levels, satisfaction levels, and physiological parameters will be assessed both before and after the procedure. The study aims to determine whether this non-pharmacological method improves postoperative pain, anxiety, patient satisfaction, and physiological parameters.

Participants needed: 44
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dokuz Eylul UniversityUpdated: Sep 28, 2026Locations: 1
Eligibility criteria

Aged 18 and older [+13]

• Under 18 years of age [+5]

Status: Recruiting

Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children

The study aims to determine whether pre-cooling and sweet-tasting solutions, alone or combined with topical anesthesia, provide better pain control during dental local anesthesia in children. It has two phases: Phase 1: Identify the children's preferred sweet-tasting solution among xylitol, monk fruit, erythritol, and honey. Phase 2: A randomized controlled trial comparing 7 groups involving pre-cooling, sweet solution, topical anesthesia, and their combinations. The primary outcome is pain measured by VAS, while secondary outcomes include SEM behavioral response, heart rate, and oxygen saturation. The planned sample is 220 children.

Participants needed: 224
Trial details
Age: 7-11Biological sex: AllType: InterventionalSponsor: British University In EgyptUpdated: Sep 22, 2026Locations: 1
Eligibility criteria

Age group 7-11 years [+2]

Failure to provide assent or consent [+3]

Status: Recruiting

the Objective of This Research is to Compare the Clinical Effectiveness of the Conventional Lingual Arch Space Maintainers With Three-dimensional Printed Space Maintainers.

the objective of this research is to compare the clinical effectiveness of the conventional lingual arch space maintainers with three-dimensional printed space maintainers.

Participants needed: 44
Trial details
Age: 7-9Biological sex: AllType: InterventionalSponsor: Suez Canal UniversityUpdated: May 15, 2026Locations: 1
Eligibility criteria

Apparently, healthy cooperative children have recently prematurely loss of more... [+7]

children exhibited poor oral hygiene, para-functional oral habits, severe crowdi... [+3]

Status: Recruiting

VR AI Meditation for Pain

This study aims to assess changes in pain and anxiety as reported by the Pain Numeric Rating Scale (PNRS) and the State-Trait Anxiety Inventory 6 (STAI-6), pre and post a guided meditation in Virtual reality. Objectives of the study are also to determine the feasibility, and patient acceptance of utilizing a LLM-generated guided meditation in VR. Our goal is to learn about any limitations of our approach and provide a pathway for future improvements in creating a VR AI therapist that is optimally aligned with the needs of users.

Participants needed: 38
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Christopher AlmarioUpdated: Nov 26, 2025Locations: 1
Eligibility criteria

18+ years of age [+3]

Unwilling and/or unable to participate [+8]