Status: Recruiting
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization. Inclisiran is a subcutaneous, twice-yearly injection that is FDA-approved as an adjunct with statin therapy and on the market to lower LDL-C in high-risk populations.
Participants needed: 6,000
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: Aug 18, 2026Locations: 133
Eligibility criteria
Signed informed consent must be obtained prior to participation in the study. [+3]
Planned future PCI or PVI [+7]