Health TrialsbyHealthPanel

Phase IB

2

Review clinical trials related to Phase IB. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Zotatifin And EIF4A Platinum Helix Inhibition In Resistant AdvancedTNBC

To find the optimal (best) recommended dose of zotatifin and carboplatin to treat patients with metastatic or recurrent TNBC.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Sep 8, 2026Locations: 1
Eligibility criteria

Participants must have histologically confirmed malignancy that is metastatic or... [+20]

Participants who have not recovered from adverse events due to prior anti-cancer... [+18]

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Status: Recruiting

Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer

To find the recommended dose of the combination of avutometinib, defactinib, and everolimus in patients with endometrial cancer that is recurrent and has abnormal RAS activity. The safety and effects of this combination will also be studied.

Participants needed: 31
Trial details
Phase: Phase 1Age: 18+Biological sex: FemaleType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Jun 29, 2026Locations: 1
Eligibility criteria

Participants must have histologically or cytologically confirmed recurrent RAS m... [+16]

Participants who are pregnant or lactating. [+26]

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