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Phenylketonuria (PKU) and Hyperphenylalaninemia

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Review clinical trials related to Phenylketonuria (PKU) and Hyperphenylalaninemia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Market Research of a Slow Release Protein Substitute for the Dietary Management of PKU

XPhePiccosMR is a prospective, single-arm, open label, observational study that aims to evaluate the acceptability and tolerability of XPhe Piccos, a slow-release, phenylalanine-free protein substitute in the form of tiny tablets, for use in the dietary management of phenylketonuria (PKU) in children aged three years and older.

Participants needed: 10
Trial details
Age: 3-18Biological sex: AllType: InterventionalSponsor: metaX Institut fuer Diatetik GmbHUpdated: Oct 9, 2026Locations: 1
Eligibility criteria

Diagnosis of PKU or HPA requiring a phenylalanine-free protein substitute. [+3]

Presence of serious concurrent illness. [+4]

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Status: Recruiting

PheCheck™ Validation Study

The goal of this observational study is to evaluate the performance of the PheCheck™ test for the rapid detection of phenylalanine (Phe) from a fingerstick sample, in patients 1 year or older with phenylketonuria (PKU) or hyperphenylalaninemia. The main objective is comparing the concentration of phenylalanine (Phe) in capillary blood with the reference method (DBS).

Participants needed: 60
Trial details
Age: 1+Biological sex: AllType: ObservationalSponsor: Aptatek BioSciences, IncUpdated: Aug 25, 2026Locations: 2
Eligibility criteria

1 year or older and able to have a fingerstick blood collected [+2]

Previous enrollment in the study and has completed 3 study visits [+1]

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