Post-Concussion Symptoms

2

Review clinical trials related to Post-Concussion Symptoms. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

HBOT Effects on First Responders' Cognition and Well-Being

The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury. The main questions it aims to answer are: 1. Do cognitive functioning and post-concussive symptoms change after 40 HBOT sessions? 2. Do symptoms of PTSD, depression, and anxiety, or quality of life, change after treatment? Approximately 54 participants will: * Complete medical and behavioral health screening. * Complete cognitive tests and questionnaires before and after treatment. * Receive 40 HBOT sessions at 2.0 atmospheres absolute (ATA), twice daily with at least four hours between sessions. All participants will receive HBOT. There is no comparison group, so the study cannot determine whether HBOT caused any observed changes.

Participants needed: 54
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Summit Hyperbarics and WellnessUpdated: Oct 1, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 75 years. [+8]

Untreated pneumothorax [+28]

Status: Recruiting

Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed recovery. This project aims to better identify biomarkers for diagnosis and prognosis and maximize recovery from mTBI.

Participants needed: 60
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: State University of New York - Upstate Medical UniversityUpdated: Oct 10, 2025Locations: 1
Eligibility criteria

18 - 55 years old [+7]

history of chronic headache diagnoses such as migraine, tension, or cluster head... [+2]