Post-traumatic Olfactory Dysfunction

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Review clinical trials related to Post-traumatic Olfactory Dysfunction. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Acupuncture for Post-traumatic Olfactory Dysfunction: A Randomized Controlled Trial

The goal of this clinical trial is to learn if acupuncture based on the "Form-Qi-Spirit" theory works to treat post-traumatic olfactory dysfunction in adults. It will also learn about the safety of this acupuncture treatment. The main questions it aims to answer are: Is the efficacy of 4-week acupuncture treatment superior to 4-week steroid treatment for post-traumatic olfactory dysfunction? What medical problems or side effects do participants have when receiving acupuncture? Researchers will compare real acupuncture plus a placebo (a look-alike pill with no active drug) to sham acupuncture (non-penetrating placebo needles) plus low-dose oral steroids (prednisone) - to see if the real acupuncture strategy works better than the steroid strategy for post-traumatic olfactory dysfunction. Participants will: Receive real acupuncture + placebo pills, OR sham acupuncture + low-dose prednisone, for 4 weeks Undergo acupuncture/sham sessions 3 times per week (12 sessions in total) Take the assigned pills daily (with tapering doses over 4 weeks) Visit the clinic for smell tests, psychological assessments, and safety checks at baseline, at 4 weeks (end of treatment), and at 12 weeks (8 weeks after treatment ends) Let me know if you need a more detailed version or any adjustments.

Participants needed: 84
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Beijing Tiantan HospitalUpdated: Sep 22, 2026Locations: 2
Eligibility criteria

Patients with post-traumatic olfactory dysfunction who meet the diagnostic crite... [+4]

Patients with a clear history of viral infection or exposure to irritant substan... [+6]

Status: Not yet recruiting

PANDORA: Evaluation of Platelet-rich Plasma in Non-tumoural Odour Disorders: a Descriptive Pilot Study.

This is a prospective, single-center, single-arm, non-comparative descriptive pilot study evaluating autologous platelet-rich plasma (PRP) injections in adults with persistent (\>6 months) non-tumoural olfactory dysfunction, either age-related degenerative olfactory dysfunction (DOD) or post-traumatic olfactory dysfunction (DOPT). Participants receive three PRP injections over 4 weeks (Day 0, Day 14, Day 28), with follow-up visits at Month 3 and Month 6 after the first injection. Olfactory function is assessed using the Sniffin' Sticks Test (TDI score). Patient-reported outcomes include SNOT-22 and a visual analog scale (VAS) for perceived olfactory impairment. Safety is assessed through adverse event collection.

Participants needed: 30
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Hospices Civils de LyonUpdated: Mar 20, 2026Locations: 1
Eligibility criteria

Adults with persistent (>6 months) non-tumoural olfactory dysfunction: age-relat... [+5]

Inflammatory rhinosinus disease (e.g., nasal polyposis) or granulomatosis with p... [+9]