Status: Recruiting
Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma
This is a multi-site study of the pharmacodynamic effects and efficacy of metformin in children and young adults with recurrent or progressive Posterior Fossa Group A (PFA) ependymoma.
Participants needed: 30
Trial details
Phase: Phase 2Age: 1-39Biological sex: AllType: InterventionalSponsor: University of California, San FranciscoUpdated: Aug 19, 2026Locations: 10
Eligibility criteria
Participants must have recurrent or progressive posterior fossa A (PFA) ependymo... [+19]
Participants with a history of diabetes mellitus or those meeting criteria for p... [+10]