Health Trials

Primary Intraocular Lymphoma

1

Review clinical trials related to Primary Intraocular Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

ZR-MTX for PIOL Phase II Trial

This is a prospective single-arm phase II study, with the purpose of evaluating the efficiency of ZR-MTX regimen (Rituximab, Zanubrutinib and methotrexate) combined with intravitreal methotrexate, then followed by minimal residual disease directed Zanubrutinib maintenance in newly-diagnosed primary intraocular lymphoma. The primary endpoint of this study is progression-free survival (PFS).

Participants needed: 47
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Peking Union Medical College HospitalUpdated: Aug 7, 2026Locations: 1
Eligibility criteria

• Newly-diagnosed primary vitreoretinal lymphoma [+6]

• primary central nervous system lymphoma involved eyes and brain [+6]

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