Health Trials

Progressive Pediatric Brain Cancer

1

Review clinical trials related to Progressive Pediatric Brain Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain Cancer

This is a open label Phase 1 study to evaluate the safety, tolerability, and pharmacokinetics of escalating oral doses of NLG802, an investigational agent intended to inhibit the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme, in combination with temozolomide chemotherapy in children with primary brain tumors.

Participants needed: 30
Trial details
Phase: Phase 1Age: 5-21Biological sex: AllType: InterventionalSponsor: Lumos PharmaUpdated: Jul 28, 2026Locations: 1
Eligibility criteria

Age must be ≥ 5 years and < 22 years. [+21]

Unable to swallow capsules. [+7]

Read more