Health Trials

Pseudophakic Bullous Keratopathy (PBK)

2

Review clinical trials related to Pseudophakic Bullous Keratopathy (PBK). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endothelial cells \[mHCECs\]), compared with a placebo injection, in participants with corneal edema caused by corneal endothelial dysfunction.

Participants needed: 121
Trial details
Phase: Phase 2Age: 21+Biological sex: AllType: InterventionalSponsor: EmmecellUpdated: Jul 29, 2026Locations: 1
Eligibility criteria

Symptomatic central corneal edema that is primarily responsible for loss of visi... [+4]

Corneal disease in either eye (other than corneal endothelial dysfunction second... [+9]

Read more
Status: Recruiting

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

The purpose of this study is to assess the efficacy and safety of single injection dose of AURN001 compared with placebo in adult participants with corneal edema secondary to corneal endothelial dysfunction.

Participants needed: 120
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Aurion BiotechUpdated: May 22, 2026Locations: 12
Eligibility criteria

Have corneal edema secondary to corneal endothelial dysfunction, requiring surge... [+2]

Have progressive corneal dystrophies or degenerations [+1]

Read more