Status: Recruiting
Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide. The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide.
Participants needed: 30
Trial details
Phase: Phase 1Age: 12-20Biological sex: AllType: InterventionalSponsor: South Plains Oncology ConsortiumUpdated: Oct 8, 2026Locations: 5
Eligibility criteria
Histologically or cytologically-confirmed Ewing sarcoma, rhabdomyosarcoma, neuro... [+6]
Clinically significant gastrointestinal disorders [+5]