Health Trials

Refractory Active Systemic Lupus Erythematosus

2

Review clinical trials related to Refractory Active Systemic Lupus Erythematosus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Clinical Study of ACG102 Injection in Patients With Refractory Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and preliminary efficacy of ACG102 administered via intravenous injection in patients with refractory active systemic lupus erythematosus (SLE)

Participants needed: 13
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyUpdated: Aug 6, 2026
Eligibility criteria

≥18 years of age at time of informed consent. [+4]

Active severe infection, including tuberculosis. [+7]

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Status: Not yet recruiting

A Study of SYS6020 Injection in Refractory Active Systemic Lupus Erythematosus

This study aimed to observe the safety and tolerability of SYS6020 in adult participants with refractory active systemic lupus erythematosus, determine the recommended dose (RD) that may be explored for subsequent studies, and preliminly evaluate the clinical efficacy of this product,and explore the pharmacokinetics and immunogenicity of SYS6020 injection in those participants.

Participants needed: 50
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd.Updated: Nov 19, 2024
Eligibility criteria

1. Age ≥18 years old, ≤70 years old; [+6]

1. Severe lupus nephritis within 8 weeks before screening; [+10]

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