Relapsed / Refractory Multiple Myeloma

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Review clinical trials related to Relapsed / Refractory Multiple Myeloma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparing Lower Versus Standard Doses of Belantamab Mafodotin With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.

This study is testing whether a lower dose of belantamab mafodotin used together with pomalidomide and dexamethasone can provide similar effectiveness with fewer side effects compared with the standard dose in patients with relapsed or refractory multiple myeloma. Participants will be randomly assigned to receive either a reduced dose or a standard dose of belantamab mafodotin in combination with pomalidomide and dexamethasone. The study will evaluate treatment response, side effects, and minimal residual disease (MRD), which is a measure of the number of myeloma cells that remain after treatment. The goal is to determine whether treatment can be optimized while maintaining disease control and reducing treatment-related toxicity.

Participants needed: 228
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Polish Myeloma ConsortiumUpdated: Aug 6, 2026
Eligibility criteria

Capable of giving signed informed consent, which includes compliance with the re... [+18]

Active plasma cell leukemia, amyloidosis, POEMS syndrome, allogeneic SCT or curr... [+25]