Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)

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Review clinical trials related to Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

This clinical trial is studying the safety and potential anti-tumor activity of an investigational drug called ARV-393 in patients diagnosed with advanced Relapsed/Refractory non-Hodgkin's lymphoma (R/R NHL) to determine if ARV-393 may be a possible treatment option. ARV-393 is thought to work by breaking down a protein present in many types of non-Hodgkins lymphomas, which may prevent, slow or stop tumor growth. This is the first time ARV-393 will be used by people. The investigational drug will be given as an oral tablet.

Participants needed: 255
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Arvinas Inc.Updated: Feb 10, 2026Locations: 17
Eligibility criteria

For Part A and B: Have relapsed/refractory NHL and >=2 prior systemic therapies,... [+6]

Current or past history of peripheral eosinophilia, hypereosinophilic syndrome (... [+12]