Rotator Cuff Tear Repair

2

Review clinical trials related to Rotator Cuff Tear Repair. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Evaluation of the Therapeutic Effect of Local Application of Tranexamic Acid in Rotator Cuff Repair

This prospective randomized controlled trial aims to evaluate the efficacy and safety of intraosseous tranexamic acid administration during arthroscopic rotator cuff repair. Eligible patients undergoing arthroscopic rotator cuff repair will be randomly assigned in a 1:1 ratio to receive either intraosseous tranexamic acid or intraosseous normal saline placebo. Tranexamic acid will be administered at a dose of 15 mg/kg through intraosseous injection into the proximal humerus after anesthesia induction. The primary outcome will be intraoperative arthroscopic visual clarity assessed using a five-grade visual clarity scoring system during different surgical stages. Secondary outcomes will include irrigation fluid volume, operative time, and frequency of irrigation pressure adjustments. Safety outcomes will include perioperative complications and laboratory assessments. This study will determine whether intraosseous tranexamic acid can improve visualization of the arthroscopic surgical field and optimize surgical conditions during rotator cuff repair.

Participants needed: 60
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Hua LuoUpdated: Jul 20, 2026Locations: 1
Eligibility criteria

Age between 18 and 80 years; [+3]

Severe open injury or infection around the surgical area; [+5]

Status: Not yet recruiting

Preoperative Versus Postoperative Interscalene Block in Arthroscopic Rotator Cuff Repair

This study is evaluating whether the timing of an interscalene nerve block affects pain control and recovery after arthroscopic rotator cuff repair surgery. An interscalene block is commonly used to reduce pain after shoulder surgery. However, it is not known whether administering the block before surgery or after surgery provides better outcomes. Participants undergoing arthroscopic rotator cuff repair are assigned to receive the interscalene block either before the surgical incision or after completion of the procedure. The study compares postoperative pain levels, opioid medication use, length of hospital stay, and ultrasound imaging quality during block administration between the two groups. Functional recovery is also assessed using patient-reported outcome measures during follow-up. The investigators hypothesize that administration of the interscalene block before surgery may provide superior early pain control and reduce postoperative opioid requirements while maintaining similar functional outcomes compared with administration after surgery.

Participants needed: 42
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Istinye UniversityUpdated: Jul 8, 2026Locations: 1Duration: 6 Months
Eligibility criteria

Adults aged 18 years or older. [+4]

Irreparable rotator cuff tears. [+8]