Rotator Cuff Tendinopathy

8

Review clinical trials related to Rotator Cuff Tendinopathy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression). The study involves adult patients attending a musculoskeletal specialty clinic. The main questions it aims to answer are: 1. Does having a structured conversation about the pros and cons of a test affect how much a person wants to have that test? 2. Does that conversation help people feel more confident and less conflicted about their decision? Researchers will compare patients who have a values-based discussion with a researcher to those who receive brief written information about the test, to see if these approaches affect how people feel about having the test. Participants will: * Read a brief scenario about a proposed diagnostic imaging test (like an X-ray, MRI, CT, or ultrasound). * Either take part in a short structured conversation or read brief information about the test. * Answer a short survey about their thoughts on the test. This study does not involve actual medical testing or affect your clinical care. It is for research purposes only.

Participants needed: 220
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Texas at AustinUpdated: Sep 22, 2026Locations: 1
Eligibility criteria

Adults (18+ years) [+3]

Cognitive or physical impairment or severe psychiatric illness that would interf...

Status: Not yet recruiting

The Effect of TECAR Therapy on Pain and Shoulder Function in Patients With Rotator Cuff Tendinopathy

Shoulder pain is one of the most common symptoms of musculoskeletal injuries; one-quarter of the general population and two-thirds of adults experience this problem at some point in their lives.Rotator cuff tendinopathy also presents as a significant socio-economic issue, affecting patients' functionality, sleep, quality of life, and work performance. TECAR therapy (Targeted Radiofrequency Therapy) is a relatively new physical therapy method. This technique aims to induce hyperthermia in deep tissues by transferring high-frequency electromagnetic energy via capacitive-resistive electric transfer (CRET). This study aims to directly compare TECAR-a relatively new treatment modality-with exercise, which is crucial in shoulder rehabilitation, by evaluating the effects of both treatments on pain reduction, shoulder function, and quality of life in patients with rotator cuff tendinopathy.

Participants needed: 36
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Ayşe Ukbe BaykutUpdated: Sep 22, 2026Locations: 1
Eligibility criteria

Individuals experiencing pain in the shoulder and/or lateral deltoid region, wit... [+2]

Full-thickness rotator cuff tear [+9]

Status: Recruiting

Intralesional Versus Perilesional 5% Dextrose Injection in Partial Rotator Cuff Tears

This prospective, randomized, double-blind controlled clinical trial aims to compare the clinical and ultrasonographic outcomes of intralesional and perilesional 5% dextrose injection in patients with partial rotator cuff tears. Eligible participants will be randomized into two parallel groups. Both groups will receive ultrasound-guided 5% dextrose injection to the supraspinatus enthesis. In addition, one group will receive intralesional 5% dextrose injection, while the other group will receive perilesional 5% dextrose injection using the peppering technique. Injections will be performed in three treatment sessions at 21-day intervals. All participants will receive a home-based exercise program after completion of the injection treatments. Clinical outcomes will be assessed at baseline, 9 weeks, and 12 weeks after treatment, and ultrasonographic outcomes will be assessed at baseline and 12 weeks.

Participants needed: 30
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Ankara City Hospital BilkentUpdated: Jul 7, 2026Locations: 1
Eligibility criteria

Diagnosis of partial rotator cuff tear by a specialist physician after appropria... [+5]

Advanced cognitive impairment or dementia preventing reliable completion of ques... [+16]

Status: Recruiting

Notch vs Midpoint Suprascapular Nerve PRF for Chronic Shoulder Pain

This study aims to compare the effects of pulsed radiofrequency (PRF) treatment of the suprascapular nerve using suprascapular notch and midpoint approaches on pain, shoulder function, and muscle strength in patients with chronic shoulder pain due to rotator cuff tendinopathy. Patients will be randomly assigned to one of the two intervention groups. Clinical evaluations will include pain assessment using the Numeric Rating Scale (NRS), functional assessment using the Shoulder Pain and Disability Index (SPADI), and quality of life assessment using the Short Form-36 (SF-36). In addition, shoulder range of motion will be measured goniometrically, muscle thickness of the supraspinatus and infraspinatus will be evaluated by ultrasonography, and shoulder muscle strength will be assessed using an isokinetic dynamometer. Assessments will be performed at baseline, 24 hours, 1 month, and 3 months after the intervention. The results of this study are expected to provide evidence regarding the optimal approach for PRF treatment of the suprascapular nerve in patients with chronic shoulder pain.

Participants needed: 32
Trial details
Age: 40-80Biological sex: AllType: InterventionalSponsor: Ankara City Hospital BilkentUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Patients aged between 40 and 80 years [+4]

Adhesive capsulitis [+9]

Status: Recruiting

Tight Control for Rotator Cuff Tendinopathy

The main objective of the study is to determine whether tight management of patients in early rotator cuff tendinopathy would lead to better clinical improvement than standard management. In a randomized study, we propose to compare two types of management, with a tight control group having one consultation per month for the first 3 months, in order to readapt or intensify management, whereas the control group will only be seen at 3 months after inclusion. We hypothesize that this close follow-up will lead to more rapid clinical improvement and reduce the transition to chronicity and the associated costs (inclusion of a medico-economic analysis taking into account, in particular, healthcare consumption and time off work).

Participants needed: 156
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Nantes University HospitalUpdated: Jan 15, 2026Locations: 8
Eligibility criteria

Age between 18 and 65 [+2]

Contraindication to steroid injections [+8]

Status: Not yet recruiting

Clinical Study on the Safety and Efficacy of Tendon Stem Progenitor Cells Therapy for Rotator Cuff Tears

Tendon injury is one of the most common sports injuries, including local tissue degeneration at the tendon insertion site following inflammation caused by long-term joint movement, friction, or strain, as well as acute traumatic tendon tears and defects of varying degrees due to sports. It is a recognized therapeutic challenge in orthopedics and sports medicine. With the increase in people's physical activities and changes in work styles, tendon injuries have become increasingly prevalent, with at least 30 million tendon injury cases annually. Meanwhile, tendon injuries pose a significant threat to the careers of many elite athletes. Currently, clinical treatments for tendon injuries mainly remain at the stages of physical therapy, surgical suture, and transplantation. Although these treatments have certain effects, their efficacy is limited-primarily because adult tendons lack complete regenerative capacity. As a result, the quality of repaired tendons is far inferior to that of normal tendons, making them prone to tendon adhesion, poor structural and mechanical properties, and frequent re-rupture. Even autologous tendon transplantation can only achieve approximately 40% of the mechanical properties of normal tendons, accompanied by excessive scar tissue formation. Current therapeutic and tissue engineering approaches can only partially improve tendon repair quality, failing to induce complete tendon repair and regeneration. Therefore, exploring new and efficient strategies for the treatment and regeneration of tendon injuries is of great significance. In recent years, cell therapy has brought new opportunities for improving the repair quality of soft tissues such as tendons. Tendon-derived cells are isolated and extracted from tendons. These cells not only possess stem cell characteristics similar to bone marrow mesenchymal stem cells but also highly express tendon-specific genes and proteins. Therefore, this study intends to first culture and expand tendon stem/progenitor cells (TSPCs) to form therapeutic agents, then apply TSPC-enhanced therapy intraoperatively to patients with rotator cuff tendinopathy, and evaluate its clinical safety and efficacy.

Participants needed: 107
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityUpdated: Jan 6, 2026
Eligibility criteria

Aged between 18 and 70 years, regardless of gender; [+3]

Tear size classified as large (3 cm to 5 cm) or massive (> 5 cm) according to th... [+17]

Status: Recruiting

Effects of TNT on Pain, ROM and Disability in Patients With RC Tendinopathy

EFFECTS OF TENDON NEUROPLASTIC TRAINING ON PAIN, RANGE OF MOTION AND DISABILITY IN PATIENTS WITH ROTATOR CUFF TENDINOPATHY

Participants needed: 38
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Nov 27, 2024Locations: 1
Eligibility criteria

Have a current shoulder complaint lasting at least three months prior to the tim... [+2]

Bilateral shoulder pain [+8]

Status: Not yet recruiting

Comparison of the Effectiveness Heavy Slow Resistance and Eccentric Training in Rotator Cuff Tendinopathy

Rotator cuff tendinopathy, also called subbracromial impingement syndrome, is one of the most important causes of anterior shoulder pain. Although exercise training is known as an effective intervention method in the treatment of rotator cuff/subacromial impingement problems, there is no definite consensus on which type of exercise is more effective. The aim of this study is to analyze and compare the effects of the Heavy Slow Resistance (HSR) training and eccentric exercise training on pain, function, supraspinatus tendon structure, muscle strength, range of motion, subjective perception of improvement and treatment satisfaction in individuals with subacromial shoulder pain associated with rotator cuff tendinopathy.

Participants needed: 20
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Mustafa Kemal UniversityUpdated: Jun 27, 2024Locations: 1
Eligibility criteria

Describing subacromial pain [+2]

Prior shoulder surgery [+8]