Running

2

Review clinical trials related to Running. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Multiphase Analysis of Next-generation Trail Footwear

This study will investigate how different advanced-foam trail-running footwear configurations affect running economy, performance, comfort, and fatigue in competitive trail runners. The project aims to determine whether footwear characteristics, particularly foam properties and stack height, influence physiological and biomechanical responses during both controlled laboratory running and real-world trail running. Approximately 30 competitive trail runners with experience in technical trail running and no musculoskeletal injury during the previous six months will participate. The study will use a two-phase experimental design. In Phase 1, participants will complete running economy assessments in three footwear conditions in randomized order. The footwear conditions will include a high-stack advanced-foam prototype, a medium-stack advanced-foam prototype, and a conventional-foam shoe. Laboratory testing will be performed during uphill and downhill treadmill running. Participants will also complete field-based running economy trials on real trail terrain at a controlled speed, followed by a short time trial to establish a representative running pace. In Phase 2, participants will complete prolonged trail-running sessions in the two advanced-foam footwear configurations on a 15-km trail course. Running economy and fatigue-related responses will be assessed repeatedly during the prolonged exercise sessions to evaluate changes in physiological and biomechanical efficiency over time. The primary physiological outcome will be running economy, assessed through oxygen consumption and energy cost. Additional outcomes will include heart rate, step frequency, step length, ground contact time, perceived exertion, comfort, perceived performance, and pacing-related measures. The study will compare laboratory and field responses to determine whether differences in running economy observed under controlled conditions are maintained during real trail running and whether footwear configuration influences the deterioration of running economy and fatigue during prolonged exercise.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Fernando González-Mohíno MayoralasUpdated: Oct 2, 2026
Eligibility criteria

Competitive trail runners. [+2]

Musculoskeletal injury in the previous 6 months.

Status: Not yet recruiting

Comparison Between Eccentric Hamstring Training and Sprint-Specific Training

The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a sprint-specific training program on hamstring muscle architecture, volume, sprint performance, strength, and power. Participants will be assigned to complete one of the 3 hamstring interventions for 10 weeks.

Participants needed: 90
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: University of Wisconsin, MadisonUpdated: Sep 29, 2026Locations: 1
Eligibility criteria

Age 18-25 years [+7]

Unable to refrain from resistance training outside the study [+5]