Severe Hypertension

1

Review clinical trials related to Severe Hypertension. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Emergency Department-Initiated Team-Based Care for Severe Hypertension

EDIT-SBP is a pragmatic, randomized clinical trial evaluating whether an emergency department (ED)-initiated team-based care program improves blood pressure control among adults discharged from the ED after severe hypertension without hypertensive emergency. Participants will be assigned 1:1 to team-based care or usual care. Team-based care includes guideline-based antihypertensive prescribing during the ED visit or within 24 hours after discharge, a cellular home blood pressure monitor, structured remote monitoring, virtual clinical pharmacist medication management through 6 months, and community health worker/patient navigator support. Usual care consists of standard ED discharge care and outpatient follow-up at the treating clinician's discretion. The primary outcome is mean systolic blood pressure measured in person at 6 months by blinded outcome assessors. Participants will be followed for 12 months for blood pressure, emergency care use, cardiovascular events, safety, quality of life, healthcare utilization, and economic outcomes.

Participants needed: 700
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Henry Ford Health SystemUpdated: Aug 20, 2026Locations: 4
Eligibility criteria

Age 18 through 85 years. [+4]

Hypertensive emergency syndrome, acute target-organ injury requiring inpatient c... [+13]