Social Isolation or Loneliness

7

Review clinical trials related to Social Isolation or Loneliness. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Social Connection Collective for Older Adults in Subsidized Housing

This study will evaluate a resident-led program designed to promote social connection among older adults living in subsidized housing communities in Baltimore. A small group of residents, called Resident Champions, will receive training and support from the research team to form a Social Connection Collective and develop activities that encourage residents to connect with one another and build peer support networks. The study will assess whether the program is feasible and acceptable to residents and will explore whether participation is associated with changes in social isolation, social connectedness, and sense of belonging. Resident Champions will participate in approximately six group sessions over about six months, help organize community activities, and complete surveys and interviews before and after the intervention. Other residents in the housing communities may complete surveys about social connections and experiences.

Participants needed: 300
Trial details
Age: 62+Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Oct 7, 2026Locations: 1
Eligibility criteria

Adults 62 years of age and older [+7]

Status: Recruiting

Evaluation of Choose to Move Replacement Ready (CTM-RR)

Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada. Recently, the investigators adapted CTM for the \>14000 people in BC who are on surgical waitlists for total knee replacement or total hip replacement (TKR/THR) for osteoarthritis (OA). The primary goals of this observational study are to describe how the adapted program, Choose to Move Replacement Ready (CTM-RR), is implemented in BC and determine if the adapted program improves health outcomes in people with hip and/or knee osteoarthritis who are on surgical waitlists for TKR/THR. The investigators will also evaluate whether any health benefits achieved by CTM-RR participants are maintained three months after they finish the program and also during the remaining time that they wait for their TKR/THR surgery. The investigators will work with referral partners from hospitals and orthopaedic clinics in BC to recruit participants into CTM-RR. Participants who enrol in CTM-RR will answer online survey questions about the program and about their physical activity, mobility, pain, function, quality of life, willingness to undergo surgery, overall perception of their joint condition, psychosocial health, self-efficacy, social isolation, loneliness, and sedentary time. CTM-RR activity coaches will also answer online survey questions about the program. CTM-RR participants, activity coaches, and referral partners will also participate in interviews about the program.

Participants needed: 210
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

Activity coach hired by the Active Aging Society (activity coaches must speak En... [+2]

non-English speaking activity coach [+1]

Status: Not yet recruiting

Talk2gether Program for Social Connection in Older Adults

The purpose of this study is to see if it is feasible to recruit and retain older adults in a, weekly phone call program delivered through the Harris County Precinct 2 Healthcare and Social Services Team and to see how participation in the program affect older adults' loneliness, social isolation, psychological well-being, and satisfaction, and what barriers or challenges arise during implementation

Participants needed: 50
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: The University of Texas Health Science Center, HoustonUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

able to provide informed consent [+2]

Need for another person to consent on the participant's behalf [+2]

Status: Recruiting

CAPABLE Care + Connect

In this evaluation scale-up research project, the investigators seek to test an implementation of CAPABLE on the infrastructure of home-based primary care for individuals who may experience social isolation and/or loneliness. These two home-based care programs may improve each other and provide opportunity to further improve quality of life for people living with disabilities and the caregivers. The purpose of this mixed methods study is to adapt and test CAPABLE, an existing evidence-based program, to a new target population with the scalable infrastructure of home-based primary care.

Participants needed: 450
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: Johns Hopkins UniversityUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

Any patient currently in JHOME [+12]

Terminally ill [+2]

Status: Not yet recruiting

The Women Veteran's Health Mission

The purpose of this study is to evaluate the impact of a customized web-based e-health program to provide online health promotion (Missions), peer support, and social connectivity to women Veterans and their families. Primary Objective • To assess participant engagement in the program including: completion rates (%) for each 6-12 week health program (Mission) defined as completing the assessments following the intervention number of login days among those who register and drop-out rates (%) defined as those who start but do not complete the program. Secondary Objectives • To assess the impact of a web-based wellness program on health metrics including: change in body weight (lbs) sleep, and chronic pain (PROMIS 29 Questionnaire) stress (PROMIS Perceived Stress) social isolation (PROMIS Social Isolation Short Form 4a). • To determine whether there is a dose-response between the number of login days into the program and changes in health metrics.

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: McGill University Health Centre/Research Institute of the McGill University Health CentreUpdated: May 27, 2026
Eligibility criteria

Canadian Woman Veteran or [+2]

Status: Recruiting

Feasibility of Choose to Move Replacement Ready

Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada. Recently, the investigators adapted CTM for the \>14000 people in BC who are on surgical waitlists for total knee replacement or total hip replacement (TKR/THR) for osteoarthritis (OA). The primary goal of this observational study is to learn if the adapted program, Choose to Move Replacement Ready (CTM-RR), is feasible to deliver to people with hip and/or knee osteoarthritis who are on surgical waitlists for TKR/THR. Participants who enrol in CTM-RR will answer online survey questions about the program and about their physical activity, mobility, pain, function, quality of life, willingness to undergo surgery, overall perception of their joint condition, psychosocial health, self-efficacy, social isolation, loneliness, and sedentary time. CTM-RR activity coaches will also answer online survey questions about the program. CTM-RR participants, activity coaches, and referral partners will also participate in interviews about the program.

Participants needed: 60
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Mar 12, 2026Locations: 1
Eligibility criteria

Activity coach hired by the Active Aging Society (activity coaches must speak En... [+2]

non-English speaking activity coach [+1]

Status: Not yet recruiting

ACOMPANYEM: A COMmunity Program Accessing Lonely, Disabled Neighbors (Young, Elder, and Midlife)

Social prescription prioritizes interventions for people at risk of social isolation or unwanted loneliness based on community assets and offers them a series of activities that can contribute to their emotional well-being as a healthy alternative to medicalized healthcare. Disabled homebound people deal with more difficulty accessing the social health assets available in the community. Volunteers from the same neighborhood may accomplish the social function of accompaniment and listening accessing them at home or walking them out to attain social prescription goals. The Community Emotional Well-Being Referent (REBEC) may enhance all of this by conducting emotional counseling and management groups for volunteers. OBJECTIVE: To evaluate the effectiveness of a community intervention of accompaniment and emotional management with volunteers on the unwanted loneliness of people with social isolation, their emotional well-being, and their quality of life. METHODOLOGY: a community-based quasi-experimental non-randomized pre-post intervention study with control group, and a qualitative study. Candidate detection by the Driving Group, composed of neighborhood organizations and the community health team, was conducted opportunistically. Recruitment of isolated individuals and volunteers was carried out, with registration based on inclusion criteria. Implementation of the multi-level intervention for volunteers and isolated individuals took place at home or by participating in community resources on the street, with parallel support groups for volunteers using REBEC. Each round of participants was followed for three months, continuing until the sample was complete. Qualitative analysis was conducted upon reaching information saturation. In cases where architectural barriers were detected, technical aids (such as portable stairlifts) were proposed, and their impact was studied.

Participants needed: 8
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaUpdated: Sep 23, 2024Locations: 1
Eligibility criteria

Disabled physical or mental homebound persons. [+2]

Impossibility of communication [+1]