To Assess the Feasibility, Visualization Capability, and Optimal Dosing of ICG Fluorescence Imaging for Intraoperative Assessment of Knee Tissue Perfusion

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Condition / disease
Location
Status: Recruiting

ICG Fluorescence in Knee Arthroscopy Study

The purpose of this study is to first evaluate whether ICG fluorescence angiography can be used to evaluate blood flow of the anterior cruciate ligament (ACL), tendons, and knee structures during an arthroscopic surgery. The secondary purpose is to evaluate differences in the blood flow in patients with varying grades of ACL tears. To determine optimal intravenous dose of SPY Agent Green and time to visualize fluorescence in tendons and structures intraoperatively during arthroscopic surgery (if primary objective is deemed yes). We hypothesize that ICG will be effective in evaluating blood flow in patients undergoing knee arthroscopy.

Participants needed: 40
Trial details
Phase: Phase 1Age: 14-89Biological sex: AllType: InterventionalSponsor: Henry Ford Health SystemUpdated: Aug 28, 2026Locations: 1
Eligibility criteria

Patients must be within ages of 14-89. Patient ages 14-17 will be included to ca... [+2]

Patient is less than 14 years of age or greater than 89 years of age [+6]