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To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer

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Review clinical trials related to To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

The purpose of this study is to evaluate the efficacy and safety of fruquintinib and pirfenidone in combination with anti-PD-1 antibody in patients with standard treatment failure of advanced or metastatic pMMR/MSS colorectal adenocarcinoma.

Participants needed: 25
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyUpdated: Aug 18, 2026Locations: 1
Eligibility criteria

Histologically confirmed diagnosis of unresectable locally advanced, recurrent o... [+4]

Previously received anti-programmed death-1 (PD-1) or its ligand (PD-L1) antibod... [+14]

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