Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA)

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Review clinical trials related to Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Impact of Regional Motor-sparing Blocks on Early Rehabilitation Following Primary Hip or Knee Arthroplasty

The purpose of this study is to determine whether a single nerve block given before surgery can help patients regain independence and mobility more quickly after planned hip or knee replacement surgery for osteoarthritis. Patients undergoing hip replacement will receive a PENG block, while patients undergoing knee replacement will receive an adductor canal block (ACB). Both procedures will be performed using ultrasound guidance. Some patients will receive a control procedure instead of the active nerve block. All participants will receive standard pain treatment and postoperative rehabilitation. The main aim of the study is to compare patients' functional independence approximately 24 hours after surgery. Other outcomes will include the ability to walk independently, performance during physiotherapy, muscle strength, pain intensity, opioid use, adverse events, and readiness for hospital discharge. Participants will be followed from the preoperative visit until 90 days after surgery. The results of this study may help determine whether these nerve blocks are a safe and effective way to support early recovery and restoration of mobility after hip or knee replacement surgery.

Participants needed: 220
Trial details
Age: 65-100Biological sex: AllType: InterventionalSponsor: Poznan University of Physical EducationUpdated: Sep 22, 2026Locations: 1
Eligibility criteria

Scheduled for elective primary unilateral total hip arthroplasty (THA) or total... [+4]

Revision arthroplasty, simultaneous bilateral arthroplasty, or arthroplasty perf... [+7]