Total Knee Arthroplasty(TKA)

3

Review clinical trials related to Total Knee Arthroplasty(TKA). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effect of Foam Rolling After Total Knee Arthroplasty

The aim of this study is to investigate the effects of foam rolling in patients who have undergone total knee arthroplasty on pain, knee mobility, leg muscle strength, the ability to sense joint position, fear of movement, walking, balance, and the ability to perform daily activities. A total of 26 patients, with 13 patients in each group, will be included in the study. Participants will be randomly assigned to two groups. One group will receive the routine rehabilitation program, while the other group will receive foam rolling in addition to the routine rehabilitation program. Foam rolling and rehabilitation exercises will be taught at the Dokuz Eylül University Orthopedics and Traumatology Outpatient Clinic, and you will be asked to perform these exercises at home. The foam rolling group will perform foam rolling 6 days per week, 2 sets per day, with 3 repetitions of 60 seconds each. The control group will not perform foam rolling and will follow the routine rehabilitation program. The standard rehabilitation program will consist of strengthening exercises in different directions for the entire leg, range-of-motion exercises, stretching exercises, and walking exercises. You will be asked to perform the exercises for 3 sets of 10 repetitions per day. The assessments in the study will be performed at the second postoperative week (test 1), sixth postoperative week (test 2), and fourteenth postoperative week (test 3). These time points are also times when you would normally visit your doctor for routine follow-up; therefore, you will not be expected to make any additional hospital visits for the study. The study will continue for 1 year, and each patient will be followed for 14 weeks. Pain will be assessed using a single-question questionnaire. Walking, functional level, and leg muscle strength will be assessed using short performance tests involving sitting-to-standing and walking activities, as well as a questionnaire. Knee joint range of motion and proprioception will be assessed by measuring the angles of your knee using a ruler-like plastic device. Fear of movement will be assessed using a short questionnaire. All assessments will take no more than 20 minutes. The results will be determined by examining whether there are differences in these measurements between the different assessment time points.

Participants needed: 26
Trial details
Age: 40+Biological sex: AllType: InterventionalSponsor: Dokuz Eylul UniversityUpdated: Oct 2, 2026Locations: 1
Eligibility criteria

Willingness to participate in the study [+2]

Body mass index (BMI) > 40 kg/m² [+5]

Status: Recruiting

Use of Cryopressotherapy in Patiens Undergoing Total Knee Replacement to Improve Clinical Outcome

The purpose of this study is to evaluate the effectiveness of cryopressotherapy in patients undergoing total knee arthroplasty by assessing clinical improvement using the KOOS at 14 days after surgery. Analysis of the knee Range of Motion (ROM) in the preoperative phase, at the predischarge visit, and at the follow-up visit for suture removal performed 14 days after surgery. Analysis of PROMs such as: Oxford Knee Score (OKS), Joint Forgotten (JF), NRS score, and SF-12. These questionnaires will be collected in the preoperative phase, at the predischarge visit, and at the follow-up visit for suture removal performed 14 days after surgery. To evaluate whether cryopressotherapy leads to an improvement in predischarge hemoglobin (Hb) levels. To assess whether cryopressotherapy reduces the circumference and subcutaneous fluid accumulation of the operated limb.

Participants needed: 78
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: I.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioUpdated: Mar 6, 2026Locations: 1
Eligibility criteria

Candidates for elective total knee arthroplasty surgery (indication determined s... [+4]

Use of medications that may interfere with muscle metabolism [+6]

Status: Recruiting

Comparison of Image Based Robotic Total Knee Arthroplasty vs Imageless Augmented Reality Assisted Total Knee Arthroplasty

This study compares the accuracy of two different techniques in placing a total knee replacement. In one technique, accurate instrument placement is facilitated by a robot, and in the other technique, augmented reality is used for correct instrument placement. Both surgical techniques are already commonly used. During both the robotic technique and the augmented reality technique, the additional information (angles - axes) obtained during the operation is used to optimize the placement of the various prosthesis components. Patients that were recently diagnosed with advanced osteoarthritis of the knee can participate in this study. This means that the cartilage of the knee is affected by wear and tear. This causes pain, stiffness and swelling resulting in reduced mobility. When non-operative treatments are insufficient in treating the osteoarthritis, surgery is proposed wherein a knee arthroplasty is performed. The goal of this study is to further optimize and personalize patient care. Additionally, the aim of the study is to investigate whether both techniques are equivalent in optimally placing the prosthesis and whether both techniques lead to comparable results.

Participants needed: 250
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Medisch Centrum LatemUpdated: Mar 24, 2025Locations: 1
Eligibility criteria

Subjects from 18 years up to 85 years old [+3]

Revision knee surgery [+5]