TP53 Y220C Mutation

1

Review clinical trials related to TP53 Y220C Mutation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

This study aims to evaluate the effects of rezatapopt on the pharmacokinetics of metformin, rosuvastatin, repaglinide, and midazolam in patients with advanced solid tumors harboring a TP53 Y220C mutation.

Participants needed: 14
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: PMV Pharmaceuticals, IncUpdated: Aug 12, 2026Locations: 5
Eligibility criteria

Written informed consent [+6]

Patients with ovarian, breast, lung, or endometrial tumors who are eligible for... [+17]