Health Trials

Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Addition of Platinum-based Chemotherapy to Tislelizumab in PD-L1high Metastatic Non-small Cell Lung Cancer With a High Tumor Burden

AIO-TRK/YMO-0425 (High Five) is a phase III, open-label randomized-controlled, multicenter study to evaluate the progression-free survival by the addition of platinum-based chemotherapy to immunotherapy (IO) compared to IO monotherapy in patients with PD-L1high mNSCLC featuring a high tumor burden.

Participants needed: 230
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: AIO-Studien-gGmbHUpdated: Jul 22, 2026Locations: 1
Eligibility criteria

Written informed consent obtained from subject and ability for subject to comply... [+11]

Presence of a condition, disease or abnormality that in the opinion of the Inves... [+6]

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Status: Recruiting

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients

Open, non-interventional, prospective, multi-center clinical research platform with the main objective to assess molecular biomarker testing, treatment and outcome of patients with NSCLC or SCLC in Germany

Participants needed: 12,400
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: AIO-Studien-gGmbHUpdated: Feb 18, 2025Locations: 1Duration: 3 Years
Eligibility criteria

Age ≥ 18 years [+12]

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Status: Recruiting

AIO-BNHO Comprehensive Clinico-genomics Database Network - AIO-BNHO CONNECT

National, retro- and prospective, observational, multicenter clinical research platform to connect clinical and genomic data of patients with advanced (locally advanced, inoperable, or metastatic) solid tumors (excluding NSCLC, SCLC, and mesothelioma) with results from multi-gene next-generation sequencing (NGS) panels (\>30 genes)

Participants needed: 3,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: AIO-Studien-gGmbHUpdated: Feb 17, 2025Locations: 3Duration: 36 Months
Eligibility criteria

Diagnosis of advanced (i.e., locally advanced, inoperable, or metastatic) solid... [+3]

Diagnosis of NSCLC/SCLC (C34) or mesothelioma (C45) [+1]

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Status: Recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome

Prospective, open, non-interventional, multi-center clinical registry study with the aim to establish a comprehensive research platform reflecting the real-world treatment landscape for recurrent/metastatic head and neck tumor patients.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: AIO-Studien-gGmbHUpdated: Nov 13, 2024Locations: 2Duration: 36 Months
Eligibility criteria

Age ≥ 18 years [+4]

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