Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Evaluation of the Risk of Heart Failure in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus

The goal of this study, performed entirely with computer programs, is to learn if using a combination of two drugs works better than using one alone, in the treatment of people with chronic kidney disease and type 2 diabetes mellitus. The main questions it aims to answer are: * How many events of heart failure, heart failure hospitalizations, and cardiovascular death happen in each group? * How do serious kidney problems progress in each of the groups? Researchers will compare reference therapy (finerenone) with a combination of finerenone and empagliflozin. There will not be human participants in this study. With the help of artificial intelligence, researchers will recreate a large population of people with chronic kidney disease and type 2 diabetes mellitus. Data on their disease, treatment, and laboratory parameters will be based on and simulated using real data from previous clinical trials conducted with real participants.

Participants needed: 50,000
Trial details
Biological sex: AllType: ObservationalSponsor: Aeterna Medical Solutions SLUpdated: Aug 19, 2026
Eligibility criteria

Patients with chronic kidney disease (eGFR 30-90 ml/min/1.73 m²) [+2]

Participants with type 1 diabetes (T1D). [+2]