Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Evaluation of SRT-017 in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer

This is a single-arm, open-label study to evaluate the safety, tolerability and preliminary anti-tumor efficacy of SRT-017 radioligand therapy in patients with PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC). All eligible participants will receive SRT-017 intravenous treatment. The primary objectives are to assess safety and tolerability. Secondary objectives include radiation dosimetry, pharmacokinetics, and preliminary antitumor activity.

Participants needed: 18
Trial details
Phase: Early Phase 1Age: 18+Biological sex: MaleType: InterventionalSponsor: Affiliated Hospital of Jiangnan UniversityUpdated: Sep 1, 2026Locations: 1
Eligibility criteria

Male participants aged 18 years or older. [+10]

Participants unable to tolerate required imaging examinations. [+17]

Status: Recruiting

PET Image Exploration of Novel Tracer [68Ga]-FAPI-JNU Imaging Studies in Patients with Malignant Tumors

To investigate the biological distribution of a new tracer 68Ga-FAPI-JNU in the primary, metastatic and normal tissues of patients with malignant tumors, and to evaluate the biological distribution of 68GA-FAPI-JNU with standardized uptake values.

Participants needed: 30
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Affiliated Hospital of Jiangnan UniversityUpdated: Jan 22, 2025Locations: 1
Eligibility criteria

The subjects sign the informed consent voluntarily and can complete the test acc... [+3]

Patients with a history or allergic constitution to any component of the develop... [+3]

Status: Recruiting

An Exploratory Study of Deep Cervical Lymphovenous Bypass (LVB) in Alzheimer's Disease

The main pathological mechanism of Alzheimer's Disease (AD) is the abnormal deposition of amyloid-beta (Aβ) and tau proteins in the brain. Recent studies indicate that these two proteins are primarily cleared through the glymphatic system-meningeal lymphatic vessels-deep cervical lymphatic vessels pathway. Lymphatic circulation disorders in elderly patients can directly lead to the abnormal deposition of these proteins. Deep cervical lymphovenous bypass can improve lymphatic circulation and effectively treat lymphedema. This project aims to verify the effectiveness of 'deep cervical lymphovenous bypass' in treating AD, offering a new surgical treatment method to improve cognitive impairment and the quality of life for AD patients.

Participants needed: 30
Trial details
Age: 60-80Biological sex: AllType: InterventionalSponsor: Affiliated Hospital of Jiangnan UniversityUpdated: Jul 12, 2024Locations: 1
Eligibility criteria

The age ranged from 60 to 80 years, and the time from initial diagnosis to enrol... [+4]

Complicated with other severe systemic underlying diseases; [+5]