Clinical trials

10

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Tears Naturale® Free and Tears Naturale® II Lubricant Eye Drops

The purpose of this post-market clinical follow-up (PMCF) study is to describe the effectiveness and safety of Tears Naturale® Free and Tears Naturale® II lubricant eye drops in subjects experiencing dry eye (DE) symptoms.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Aug 19, 2026Locations: 6
Eligibility criteria

Able to read, understand, and sign an Institutional Review Board (IRB)/Independe... [+4]

Any known allergic reactions to the study products or its ingredients. [+4]

Status: Not yet recruiting

UNITY DX Cornea Study

The purpose of this study is to validate the clinical measurement performance of an investigational biometer. Subjects will undergo multiple measurements of the eye, and the agreement, repeatability, and reproducibility of corneal and epithelial thickness maps will be evaluated.

Participants needed: 110
Trial details
Age: 22+Biological sex: AllType: ObservationalSponsor: Alcon ResearchUpdated: Aug 17, 2026Locations: 1
Eligibility criteria

Able to understand and sign an Institutional Review Board approved informed cons... [+3]

Unable to fixate due to nystagmus or other eye movement abnormality, such as sig... [+3]

Status: Recruiting

Surgical Procedure Efficiency Evaluation stuDy

The purpose of this real-world evidence study is to compare surgical procedure times for UNITY® VCS and CONSTELLATION® Vision System.

Participants needed: 180
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Alcon ResearchUpdated: Aug 13, 2026Locations: 1
Eligibility criteria

Able to understand and sign an informed consent form (ICF) that has been approve... [+2]

Unplanned/emergency phacovitrectomy. [+3]

Status: Recruiting

Hydrus® Microstent New Enrollment Post-Approval Study

The purpose of this post-approval study is to evaluate the rate of Hydrus Microstent malposition and associated clinical sequelae occurring within 24 months post-operation. Qualified subjects will undergo uncomplicated cataract surgery with placement of a monofocal intraocular lens (IOL), followed by implantation of the Hydrus Microstent.

Participants needed: 545
Trial details
Age: 45+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Jul 14, 2026Locations: 22
Eligibility criteria

An operable, age-related cataract with best corrected visual acuity (BCVA) of 20... [+3]

Closed angle forms of glaucoma; [+6]

Status: Not yet recruiting

Clinical Evaluation of a Novel Trifocal IOL

The purpose of this study is to understand the visual outcomes of the investigational intraocular lens (IOL) Model LPYWT0 when compared to the commercially marketed Clareon PanOptix Pro IOL Model PXYWT0.

Participants needed: 66
Trial details
Age: 22+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Jul 8, 2026Locations: 4
Eligibility criteria

The calculated power needed for the artificial lens (IOL) must be between +15.0... [+3]

Clinically significant corneal diseases which may, according to the investigator... [+4]

Status: Not yet recruiting

An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults

The purpose of this study is to evaluate the efficacy and safety of an investigational ophthalmic solution in adults with ocular redness caused by minor eye irritations.

Participants needed: 178
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Capable of giving signed informed consent and comply with the requirements liste... [+4]

Known contraindications or sensitivity to the use of any of the study treatment(... [+6]

Status: Not yet recruiting

Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults

The purpose of this study is to evaluate the efficacy and safety of an investigational ophthalmic solution in adults with ocular redness due to minor eye irritations.

Participants needed: 230
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Capable of giving signed informed consent and comply with the requirements liste... [+4]

Known contraindications or sensitivity to the use of any of the investigational... [+6]

Status: Recruiting

Clareon TruPlus Study

The purpose of this research study is to generate safety and performance data for Clareon TruPlus Monofocal Intraocular Lenses (IOLs). IOLs are medical devices that are implanted in the eye during cataract surgery to restore clear vision after the cloudy natural lens has been removed. IOLs are intended to remain in the eyes for the duration of the patient's lifetime.

Participants needed: 122
Trial details
Age: 22+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: Jun 3, 2026Locations: 5
Eligibility criteria

Diagnosed with bilateral cataracts and planned bilateral cataract extraction by... [+3]

Age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, and othe... [+2]

Status: Recruiting

Capella Scientia Development Study

This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Alcon ResearchUpdated: May 26, 2026Locations: 4
Eligibility criteria

Able to understand and sign an IRB/IEC approved consent form; [+3]

Women of child-bearing potential; [+5]

Status: Recruiting

Feasibility Study of an Accommodating IOL Design

The purpose of this clinical study is to assess safety and explore usability and effectiveness of the test product, AAL-FAIOL. This study will be conducted in Central America.

Participants needed: 85
Trial details
Age: 22+Biological sex: AllType: InterventionalSponsor: Alcon ResearchUpdated: May 19, 2026Locations: 4
Eligibility criteria

Able to understand and sign an Informed Consent Form. [+4]

Women of childbearing potential who are pregnant, intend to become pregnant duri... [+4]