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Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in Participants With Mild Hepatic Impairment Compared With Participants With Normal Hepatic Function

This study is designed to assess the safety, tolerability and pharmacokinetics of ABI-6250 in participants with mild hepatic impairment compared with participants with normal hepatic function.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-80Biological sex: AllType: InterventionalSponsor: Assembly BiosciencesUpdated: Oct 1, 2026Locations: 1
Eligibility criteria

Participant is willing and able to provide written informed consent, is availabl... [+11]

Child-Pugh score >6 at Screening. [+32]

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Status: Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Efficacy of ABI-6250 in Participants With Chronic Hepatitis D Virus Infection

This study is designed to assess safety, pharmacokinetics, and efficacy ABI-6250 in participants with Chronic Hepatitis D Virus Infection.

Participants needed: 80
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Assembly BiosciencesUpdated: Aug 13, 2026Locations: 22
Eligibility criteria

Participant has a body mass index ≥18.0 and <35.0 kg/m2 at Screening [+2]

Participant has a current coinfection with acute hepatitis A virus (HAV), hepati... [+3]

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