Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

The purpose of this clinical investigation is to evaluate the safety of the ColoSeal ICD System by evaluating its effectiveness in reducing the stoma creation rate and by comparing the rate of major complications to current standard of care for rectal cancer surgery with a diverting ostomy.

Participants needed: 250
Trial details
Age: 22-75Biological sex: AllType: InterventionalSponsor: Averto Medical, Inc.Updated: Aug 21, 2026Locations: 9
Eligibility criteria

Subject is 22-75 years of age at screening and is diagnosed with rectal cancer. [+7]

Subject at the time of baseline screening is not planned to have ostomy reversal... [+29]

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Status: Recruiting

ColoSeal™ ICD System Safety and Feasibility Study

The purpose of this clinical investigation is to evaluate the safety and feasibility of the ColoSeal ICD System in a prospective, multicenter, single-arm study. The ColoSeal ICD System is intended to be used to protect a damaged segment of colon such as a surgical anastomosis, anastomosis leak, or perforation from contact with fecal flow for up to 14 days. The device will be evaluated in adult patients with rectal and rectosigmoid cancer undergoing a resection with a colorectal anastomosis.

Participants needed: 90
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Averto Medical, Inc.Updated: Jun 23, 2026Locations: 3
Eligibility criteria

Subject is 18-65 years of age at screening, or subject is 66-70 years of age at... [+4]

Subject with a life expectancy < 1 year [+23]

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