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Condition / disease
Location
Status: Not yet recruiting

Urolithin A Supplementation During Pulmonary Rehabilitation in Patients With COPD

SUPRA-COPD is a multicenter triple-blind, parallel arm, placebo-controlled randomized controlled trial investigating the efficacy and safety of Urolithin A supplementation during pulmonary rehabilitation in patients with COPD. The goal of the SUPRA-COPD study is to investigate whether Urolithin A supplementation during pulmonary rehabilitation in patients with COPD improves exercise tolerance, along with several other clinically important outcomes, above and beyond pulmonary rehabilitation participation alone. Study participation will be approximately 14 weeks and involves in-person visits evaluating exercise tolerance before and after PR.

Participants needed: 198
Trial details
Phase: Phase 2Age: 40+Biological sex: AllType: InterventionalSponsor: Bryan A. RossUpdated: Oct 13, 2026
Eligibility criteria

Males and females, aged >40, former smokers with ≥10 pack-year smoking history [+2]

Inability to participate in a standard PR program [+13]