Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic Hypoparathyroidism

The aim of the study is to evaluate the efficacy, safety, and tolerability of orally administered encaleret tablets in participants with chronic hypoparathyroidism (HP).

Participants needed: 160
Trial details
Phase: Phase 3Age: 16+Biological sex: AllType: InterventionalSponsor: Calcilytix Therapeutics, Inc., a BridgeBio companyUpdated: Sep 16, 2026Locations: 5
Eligibility criteria

Participants must have had a clinically confirmed diagnosis of chronic HP, with... [+9]

Genetically confirmed diagnosis of autosomal dominant hypocalcemia type 1 (ADH1)... [+4]

Status: Recruiting

Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1)

The overall objective of this study is to evaluate the pharmacokinetics (PK), efficacy, and safety of encaleret in pediatric participants from birth to 17 years of age with ADH1.

Participants needed: 28
Trial details
Phase: Phase 2, Phase 3Age: 0-17Biological sex: AllType: InterventionalSponsor: Calcilytix Therapeutics, Inc., a BridgeBio companyUpdated: Apr 22, 2026Locations: 6
Eligibility criteria

Provide written informed consent (if legally permitted), or have written informe... [+3]

History of thyroid or parathyroid surgery [+6]