Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Ureterolysis in Laparoscopic Total Hysterectomy: Routine Approach

This randomized controlled trial will compare routine bilateral ureterolysis with selective ureterolysis during total laparoscopic hysterectomy for benign gynecological conditions. Participants will be allocated to either routine ureter identification and dissection before uterine vessel ligation or selective ureterolysis performed only when predefined intraoperative safety triggers are present. The primary outcome will be the incidence of recognized and unrecognized ureteric injury, while secondary outcomes will include operative time, blood loss, other perioperative complications, conversion to laparotomy, length of hospital stay, and postoperative recovery.

Participants needed: 35,000
Trial details
Age: 35-70Biological sex: FemaleType: InterventionalSponsor: ClinAmygateUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Women aged ≥18 years. [+3]

Suspected or confirmed gynecological malignancy. [+6]

Status: Not yet recruiting

Routine Versus Selective Ureterolysis During Total Laparoscopic Hysterectomy for Benign Conditions

To evaluate whether routine ureterolysis during Total Laparoscopic Hysterectomy for benign gynecologic conditions affects operative efficiency and perioperative safety compared with a selective ureterolysis approach.

Participants needed: 100
Trial details
Age: 35-70Biological sex: FemaleType: InterventionalSponsor: ClinAmygateUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Previous pelvic radiation [+6]