Health TrialsbyHealthPanel

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult and adolescent participants receiving home Total Parenteral Nutrition (TPN) via Central Venous Catheter (CVC) compared with heparin.

Participants needed: 200
Trial details
Phase: Phase 3Age: 12+Biological sex: AllType: InterventionalSponsor: CorMedix TherapeuticsUpdated: Sep 25, 2026Locations: 24
Eligibility criteria

Participants who are resident within study site's country. [+11]

Any participant unable or not willing to sign inform consent or, in the case of... [+20]

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Status: Recruiting

Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

This study is a post-marketing approval requirement to assess the safety and time to Catheter-related Bloodstream Infections (CRBSI) of DefenCath in pediatric population (birth to less than 18 years of age) who are on chronic HD for kidney failure.

Participants needed: 36
Trial details
Phase: Phase 4Age: Up to 17Biological sex: AllType: InterventionalSponsor: CorMedix TherapeuticsUpdated: Sep 25, 2026Locations: 6
Eligibility criteria

The investigator, or a person designated by the investigator, will obtain writte... [+16]

Any participant who is currently receiving systemic antibiotics. Topical antibio... [+18]

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